Tissue expression of RPP21 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	RPP21
Gene description	Ribonuclease P/MRP 21kDa subunit
Protein class	Enzymes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Mixed
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Mixed
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	RPP21 (HGNC Symbol)
Synonyms	C6orf135, Em:AB014085.3, FLJ22638
Description	Ribonuclease P/MRP 21kDa subunit (HGNC Symbol)
Entrez gene summary	RPP21 is a protein subunit of nuclear ribonuclease P, which processes the 5-prime leader sequence of precursor tRNAs (Jarrous et al., 2001 [PubMed 11497433]).[supplied by OMIM, Jan 2009]
Chromosome	6
Cytoband	p22.1
Chromosome location (bp)	30345131 - 30346884
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000241370 (version 83.38)
Entrez gene	79897
UniProt	Q9H633 (UniProt - Evidence at protein level)
neXtProt	NX_Q9H633
Antibodypedia	RPP21 antibodies

PROTEIN BROWSER

RPP21-001	RPP21-002	RPP21-003	RPP21-006

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RPP21-001 ENSP00000403833 ENST00000442966	Q9H633 [Direct mapping] Ribonuclease P protein subunit p21 Show all	Enzymes ENZYME proteins Hydrolases Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004526 [ribonuclease P activity] GO:0005654 [nucleoplasm] GO:0005655 [nucleolar ribonuclease P complex] GO:0008033 [tRNA processing] GO:0010467 [gene expression] GO:0042493 [response to drug] GO:0046872 [metal ion binding] GO:0090501 [RNA phosphodiester bond hydrolysis] GO:0090502 [RNA phosphodiester bond hydrolysis, endonucleolytic] Show all	154 aa 17.6 kDa	No	0
RPP21-002 ENSP00000397778 ENST00000436442	Q9H633 [Direct mapping] Ribonuclease P protein subunit p21 Show all	Enzymes ENZYME proteins Hydrolases Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004526 [ribonuclease P activity] GO:0005654 [nucleoplasm] GO:0005655 [nucleolar ribonuclease P complex] GO:0008033 [tRNA processing] GO:0010467 [gene expression] GO:0042493 [response to drug] GO:0046872 [metal ion binding] GO:0090501 [RNA phosphodiester bond hydrolysis] GO:0090502 [RNA phosphodiester bond hydrolysis, endonucleolytic] Show all	144 aa 16.5 kDa	No	0
RPP21-003 ENSP00000394320 ENST00000428040	Q9H633 [Direct mapping] Ribonuclease P protein subunit p21 Show all	Enzymes ENZYME proteins Hydrolases Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004526 [ribonuclease P activity] GO:0005654 [nucleoplasm] GO:0005655 [nucleolar ribonuclease P complex] GO:0008033 [tRNA processing] GO:0010467 [gene expression] GO:0042493 [response to drug] GO:0046872 [metal ion binding] GO:0090501 [RNA phosphodiester bond hydrolysis] GO:0090502 [RNA phosphodiester bond hydrolysis, endonucleolytic] Show all	177 aa 20 kDa	No	0
RPP21-006 ENSP00000409799 ENST00000433076	Q9H633 [Direct mapping] Ribonuclease P protein subunit p21 Show all	Enzymes ENZYME proteins Hydrolases Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004526 [ribonuclease P activity] GO:0005654 [nucleoplasm] GO:0005655 [nucleolar ribonuclease P complex] GO:0008033 [tRNA processing] GO:0010467 [gene expression] GO:0042493 [response to drug] GO:0046872 [metal ion binding] GO:0090501 [RNA phosphodiester bond hydrolysis] GO:0090502 [RNA phosphodiester bond hydrolysis, endonucleolytic] Show all	162 aa 18.4 kDa	No	0