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Most cancer cells were negative. A few cases of skin, breast, cervical and urothelial cancers displayed weak to moderate positivity. Among skin cancers, basal cell carcinomas were negative, while the squamous carcinomas were positive.
Serpin peptidase inhibitor, clade B (ovalbumin), member 10 (HGNC Symbol)
Entrez gene summary
This gene is a member of the serpin peptidase inhibitor, clade B family and is found in a cluster of other similar genes on chromosome 18. The protein encoded by this gene appears to help control the regulation of protease functions during hematopoiesis. Variations in this gene may increase the risk of prostate cancer. [provided by RefSeq, Dec 2015]
SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
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GO:0002230 [positive regulation of defense response to virus by host] GO:0004867 [serine-type endopeptidase inhibitor activity] GO:0005615 [extracellular space] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0010951 [negative regulation of endopeptidase activity] GO:0098779 [mitophagy in response to mitochondrial depolarization]