Expression of CFAP57 in cancer - Summary

CANCER ATLAS

Gene description

Cilia and flagella associated protein 57

Protein class

Predicted intracellular proteins, Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA002736	HPA028623

GENE INFORMATION
Gene name	CFAP57 (HGNC Symbol)
Synonyms	FLJ32000, WDR65
Description	Cilia and flagella associated protein 57 (HGNC Symbol)
Entrez gene summary	This protein encoded by this gene belongs to the WD repeat-containing family of proteins, which function in the formation of protein-protein complexes in a variety of biological pathways. This family member is thought to function in craniofacial development, possibly in the fusion of lip and palate. A missense mutation in this gene is associated with Van der Woude syndrome 2. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011]
Chromosome	1
Cytoband	p34.2
Chromosome location (bp)	43172149 - 43254358
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000243710 (version 83.38)
Entrez gene	149465
UniProt	Q96MR6 (UniProt - Evidence at transcript level)
neXtProt	NX_Q96MR6
Antibodypedia	CFAP57 antibodies

PROTEIN BROWSER

CFAP57-001	CFAP57-002	CFAP57-004	CFAP57-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CFAP57-001 ENSP00000435310 ENST00000528956	Q96MR6 [Direct mapping] Cilia- and flagella-associated protein 57 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] Show all	698 aa 78.2 kDa	No	1
CFAP57-002 ENSP00000361570 ENST00000372492	Q96MR6 [Direct mapping] Cilia- and flagella-associated protein 57 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] Show all	1250 aa 145 kDa	No	0
CFAP57-004 ENSP00000434133 ENST00000529956	E9PRV3 [Direct mapping] Cilia- and flagella-associated protein 57 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] Show all	166 aa 19.1 kDa	No	0
CFAP57-201 ENSP00000479773 ENST00000610710	A0A087WVY5 [Direct mapping] Cilia- and flagella-associated protein 57 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] Show all	1283 aa 149 kDa	No	0