Expression of ZNF674 in cancer - Summary - The Human Protein Atlas

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ZNF674

TISSUE

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CELL

CANCER

CANCER ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

CANCER ATLAS

Gene description

Zinc finger protein 674

Protein class

Predicted intracellular proteins, Transcription factors

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

STAINING SUMMARY

HPA031026

GENE INFORMATION
Gene name	ZNF674 (HGNC Symbol)
Synonyms	MRX92, ZNF673B
Description	Zinc finger protein 674 (HGNC Symbol)
Entrez gene summary	This gene encodes a zinc finger protein with an N-terminal Kruppel-associated box-containing (KRAB) domain and 11 Kruppel-type C2H2 zinc finger domains. Like other zinc finger proteins, this gene may function as a transcription factor. This gene resides on an area of chromosome X that has been implicated in nonsyndromic X-linked mental retardation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2010]
Chromosome	X
Cytoband	p11.3
Chromosome location (bp)	46497727 - 46545457
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000251192 (version 83.38)
Entrez gene	641339
UniProt	Q2M3X9 (UniProt - Evidence at transcript level)
neXtProt	NX_Q2M3X9
Antibodypedia	ZNF674 antibodies

PROTEIN BROWSER

ZNF674-001	ZNF674-004	ZNF674-008

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ZNF674-001 ENSP00000429148 ENST00000523374	Q2M3X9 [Direct mapping] Zinc finger protein 674 Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Show all	GO:0003676 [nucleic acid binding] GO:0003677 [DNA binding] GO:0005622 [intracellular] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	581 aa 67.2 kDa	No	0
ZNF674-004 ENSP00000428248 ENST00000414387	Q2M3X9 [Direct mapping] Zinc finger protein 674 Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Show all	GO:0003676 [nucleic acid binding] GO:0003677 [DNA binding] GO:0005622 [intracellular] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	575 aa 66.5 kDa	No	0
ZNF674-008 ENSP00000429646 ENST00000518708	E5RHV3 [Direct mapping] Zinc finger protein 674 Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0005622 [intracellular] GO:0006355 [regulation of transcription, DNA-templated] Show all	100 aa 11.1 kDa	No	0

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.