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ZNF674

GENERAL INFORMATION

Gene name

 ZNF674

Gene description

 Zinc finger protein 674

Protein class

 Predicted intracellular proteins
Transcription factors

Predicted localization

 Intracellular

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Mixed
GTEx:Mixed
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Nuclear expression in several tissues, including testis.

DATA RELIABILITY

Data reliability
description

 Pending external verification.

Reliability score

 Uncertain based on 1 antibody.
HPA031026
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Stomach

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 ZNF674 (HGNC Symbol)

Synonyms

 MRX92, ZNF673B

Description

 Zinc finger protein 674 (HGNC Symbol)

Entrez gene summary

 This gene encodes a zinc finger protein with an N-terminal Kruppel-associated box-containing (KRAB) domain and 11 Kruppel-type C2H2 zinc finger domains. Like other zinc finger proteins, this gene may function as a transcription factor. This gene resides on an area of chromosome X that has been implicated in nonsyndromic X-linked mental retardation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2010]

Chromosome

 X

Cytoband

 p11.3

Chromosome location (bp)

 46497727 - 46545457

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000251192 (version 83.38)

Entrez gene

 641339

UniProt

 Q2M3X9 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q2M3X9

Antibodypedia

 ZNF674 antibodies

PROTEIN BROWSER
ZNF674-001
ZNF674-004
ZNF674-008

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ZNF674-001
ENSP00000429148
ENST00000523374
Q2M3X9 [Direct mapping]
Zinc finger protein 674
Show all
Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
Show all
GO:0003676 [nucleic acid binding]
GO:0003677 [DNA binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0046872 [metal ion binding]
Show all
 581 aa
67.2 kDa 		No 0
ZNF674-004
ENSP00000428248
ENST00000414387
Q2M3X9 [Direct mapping]
Zinc finger protein 674
Show all
Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
Show all
GO:0003676 [nucleic acid binding]
GO:0003677 [DNA binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0046872 [metal ion binding]
Show all
 575 aa
66.5 kDa 		No 0
ZNF674-008
ENSP00000429646
ENST00000518708
E5RHV3 [Direct mapping]
Zinc finger protein 674
Show all
Predicted intracellular proteins
Show all
GO:0003676 [nucleic acid binding]
GO:0005622 [intracellular]
GO:0006355 [regulation of transcription, DNA-templated]
Show all
 100 aa
11.1 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.