Fields »
ABOUT
HELP
BLOG
FOXD1

Please wait until image is loaded before changing channels

GENERAL INFORMATION

Gene name

 FOXD1

Gene description

 Forkhead box D1

Protein class

 Predicted intracellular proteins
Transcription factors

Predicted localization

 Intracellular

Number of transcripts

 1
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

Summary

RNA cell category

 Cell line enhanced (U-138 MG)

Protein evidence

 Evidence at transcript level

Main location

 Not available

DATA RELIABILITY

Reliability score

 Pending cell analysis.

ASSAYS
RNA expression

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (U-138 MG)
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

GENE INFORMATION

Gene name

 FOXD1 (HGNC Symbol)

Synonyms

 FKHL8, FREAC4

Description

 Forkhead box D1 (HGNC Symbol)

Entrez gene summary

 This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. Studies of the orthologous mouse protein indicate that it functions in kidney development by promoting nephron progenitor differentiation, and it also functions in the development of the retina and optic chiasm. It may also regulate inflammatory reactions and prevent autoimmunity. [provided by RefSeq, Apr 2014]

Chromosome

 5

Cytoband

 q13.2

Chromosome location (bp)

 73444827 - 73448362

Protein evidence

 Evidence at transcript level (all genes)

Ensembl

 ENSG00000251493 (version 83.38)

Entrez gene

 2297

UniProt

 Q16676 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q16676

Antibodypedia

 FOXD1 antibodies

PROTEIN BROWSER
FOXD1-003

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
FOXD1-003
ENSP00000481581
ENST00000615637
Q16676 [Direct mapping]
Forkhead box protein D1
Show all
Predicted intracellular proteins
Transcription factors
   Helix-turn-helix domains
Show all
GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding]
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006357 [regulation of transcription from RNA polymerase II promoter]
GO:0008301 [DNA binding, bending]
GO:0009653 [anatomical structure morphogenesis]
GO:0010628 [positive regulation of gene expression]
GO:0030154 [cell differentiation]
GO:0030513 [positive regulation of BMP signaling pathway]
GO:0043565 [sequence-specific DNA binding]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0060678 [dichotomous subdivision of terminal units involved in ureteric bud branching]
GO:0072213 [metanephric capsule development]
GO:0072267 [metanephric capsule specification]
GO:0090184 [positive regulation of kidney development]
Show all
 465 aa
46.1 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.