Tissue expression of FOXD1 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	FOXD1
Gene description	Forkhead box D1
Protein class	Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enhanced (testis)
GTEx:	Tissue enhanced (testis)
FANTOM5:	Tissue enhanced (retina)

Protein evidence

Evidence at transcript level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (testis)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (testis)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (retina)

GENE INFORMATION
Gene name	FOXD1 (HGNC Symbol)
Synonyms	FKHL8, FREAC4
Description	Forkhead box D1 (HGNC Symbol)
Entrez gene summary	This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. Studies of the orthologous mouse protein indicate that it functions in kidney development by promoting nephron progenitor differentiation, and it also functions in the development of the retina and optic chiasm. It may also regulate inflammatory reactions and prevent autoimmunity. [provided by RefSeq, Apr 2014]
Chromosome	5
Cytoband	q13.2
Chromosome location (bp)	73444827 - 73448362
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000251493 (version 83.38)
Entrez gene	2297
UniProt	Q16676 (UniProt - Evidence at transcript level)
neXtProt	NX_Q16676
Antibodypedia	FOXD1 antibodies

PROTEIN BROWSER

FOXD1-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FOXD1-003 ENSP00000481581 ENST00000615637	Q16676 [Direct mapping] Forkhead box protein D1 Show all	Predicted intracellular proteins Transcription factors Helix-turn-helix domains Show all	GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0003677 [DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0008301 [DNA binding, bending] GO:0009653 [anatomical structure morphogenesis] GO:0010628 [positive regulation of gene expression] GO:0030154 [cell differentiation] GO:0030513 [positive regulation of BMP signaling pathway] GO:0043565 [sequence-specific DNA binding] GO:0045892 [negative regulation of transcription, DNA-templated] GO:0060678 [dichotomous subdivision of terminal units involved in ureteric bud branching] GO:0072213 [metanephric capsule development] GO:0072267 [metanephric capsule specification] GO:0090184 [positive regulation of kidney development] Show all	465 aa 46.1 kDa	No	0