Cell atlas - SALL3 - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

SALL3

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

Please wait until image is loaded before changing channels

GENERAL INFORMATION
Gene name	SALL3
Gene description	Spalt-like transcription factor 3
Protein class	Plasma proteins Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	5
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Group enriched (NTERA-2, HEK 293)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Group enriched (NTERA-2, HEK 293) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	SALL3 (HGNC Symbol)
Synonyms	ZNF796
Description	Spalt-like transcription factor 3 (HGNC Symbol)
Entrez gene summary	This gene encodes a sal-like C2H2-type zinc-finger protein, and belongs to a family of evolutionarily conserved genes found in species as diverse as Drosophila, C. elegans, and vertebrates. Mutations in some of these genes are associated with congenital disorders in human, suggesting their importance in embryonic development. This protein binds to DNA methyltransferase 3 alpha (DNMT3A), and reduces DNMT3A-mediated CpG island methylation. It is suggested that silencing of this gene, resulting in acceleration of DNA methylation, may have a role in oncogenesis. [provided by RefSeq, Oct 2011]
Chromosome	18
Cytoband	q23
Chromosome location (bp)	78980275 - 79002677
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000256463 (version 83.38)
Entrez gene	27164
UniProt	Q9BXA9 (UniProt - Evidence at protein level)
neXtProt	NX_Q9BXA9
Antibodypedia	SALL3 antibodies

PROTEIN BROWSER

SALL3-001	SALL3-002	SALL3-003	SALL3-006	SALL3-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SALL3-001 ENSP00000441823 ENST00000537592	Q9BXA9 [Direct mapping] Sal-like protein 3 Show all	Predicted intracellular proteins Plasma proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Ezkurdia et al 2014) Show all	GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005634 [nucleus] GO:0006355 [regulation of transcription, DNA-templated] GO:0006366 [transcription from RNA polymerase II promoter] GO:0007165 [signal transduction] GO:0021891 [olfactory bulb interneuron development] GO:0022008 [neurogenesis] GO:0035136 [forelimb morphogenesis] GO:0035137 [hindlimb morphogenesis] GO:0043565 [sequence-specific DNA binding] GO:0044212 [transcription regulatory region DNA binding] GO:0045879 [negative regulation of smoothened signaling pathway] GO:0046872 [metal ion binding] Show all	1300 aa 135.3 kDa	No	0
SALL3-002 ENSP00000458360 ENST00000575389	Q9BXA9 [Direct mapping] Sal-like protein 3 Show all	Predicted intracellular proteins Plasma proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Ezkurdia et al 2014) Show all	GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005634 [nucleus] GO:0006355 [regulation of transcription, DNA-templated] GO:0006366 [transcription from RNA polymerase II promoter] GO:0007165 [signal transduction] GO:0022008 [neurogenesis] GO:0043565 [sequence-specific DNA binding] GO:0044212 [transcription regulatory region DNA binding] GO:0046872 [metal ion binding] Show all	1228 aa 127.3 kDa	No	0
SALL3-003 ENSP00000461451 ENST00000573324	I3L3L8 [Direct mapping] Sal-like protein 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0046872 [metal ion binding] Show all	150 aa 15.2 kDa	No	0
SALL3-006 ENSP00000439975 ENST00000536229	Q9BXA9 [Direct mapping] Sal-like protein 3 Show all	Predicted intracellular proteins Plasma proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Ezkurdia et al 2014) Show all	GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005634 [nucleus] GO:0006355 [regulation of transcription, DNA-templated] GO:0006366 [transcription from RNA polymerase II promoter] GO:0007165 [signal transduction] GO:0022008 [neurogenesis] GO:0043565 [sequence-specific DNA binding] GO:0044212 [transcription regulatory region DNA binding] GO:0046872 [metal ion binding] Show all	1095 aa 113.2 kDa	No	0
SALL3-201 ENSP00000481352 ENST00000616649	A0A087WXW6 [Direct mapping] Sal-like protein 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0046872 [metal ion binding] Show all	960 aa 101.7 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.