Cell atlas - GPR142 - The Human Protein Atlas

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GPR142

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cell Junctions
	Cytosol
	Plasma membrane

Human cell
	Cytosol
	Plasma Membrane

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GENERAL INFORMATION
Gene name	GPR142
Gene description	G protein-coupled receptor 142
Protein class	G-protein coupled receptors Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the plasma membrane & cytosol. In addition localized to the cell junctions.
RNA cell category	Not detected
Protein evidence	Evidence at transcript level
Main location	Localized to the Plasma membrane (uncertain), Cytosol (uncertain)
Additional location	In addition localized to the Cell Junctions (uncertain)

DATA RELIABILITY
Reliability score	Uncertain based on 1 antibody. HPA031392
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Not detected Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the plasma membrane & cytosol. In addition localized to the cell junctions.

Main location

Plasma membrane (uncertain), Cytosol (uncertain)

Additional location

Cell Junctions (uncertain)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA031392	A-431	Plasma membrane
			Cell Junctions
			Cytosol
	HPA031392	U-2 OS	Plasma membrane
	HPA031392	U-2 OS	Cytosol
	HPA031392	U-251 MG	Plasma membrane
	HPA031392	U-251 MG	Cytosol

GENE INFORMATION
Gene name	GPR142 (HGNC Symbol)
Synonyms	PGR2
Description	G protein-coupled receptor 142 (HGNC Symbol)
Entrez gene summary	GPR142 is a member of the rhodopsin family of G protein-coupled receptors (GPRs) (Fredriksson et al., 2003 [PubMed 14623098]).[supplied by OMIM, Mar 2008]
Chromosome	17
Cytoband	q25.1
Chromosome location (bp)	74367407 - 74372622
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000257008 (version 83.38)
Entrez gene	350383
UniProt	Q7Z601 (UniProt - Evidence at transcript level)
neXtProt	NX_Q7Z601
Antibodypedia	GPR142 antibodies

PROTEIN BROWSER

GPR142-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GPR142-002 ENSP00000335158 ENST00000335666	Q7Z601 [Direct mapping] Probable G-protein coupled receptor 142 Show all	G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Show all	GO:0004930 [G-protein coupled receptor activity] GO:0005737 [cytoplasm] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0008528 [G-protein coupled peptide receptor activity] GO:0016021 [integral component of membrane] GO:0030054 [cell junction] Show all	462 aa 51.1 kDa	No	7

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.