Expression of TSPY1 in cancer - Summary

CANCER ATLAS

Gene description

Testis specific protein, Y-linked 1

Protein class

Disease related genes, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

STAINING SUMMARY

HPA049384

GENE INFORMATION
Gene name	TSPY1 (HGNC Symbol)
Synonyms	CT78, TSPY
Description	Testis specific protein, Y-linked 1 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is found only in testicular tissue and may be involved in spermatogenesis. Approximately 35 copies of this gene are present in humans, but only a single, nonfunctional orthologous gene is found in mouse. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
Chromosome	Y
Cytoband	p11.2
Chromosome location (bp)	9466955 - 9490081
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000258992 (version 83.38)
Entrez gene	7258
UniProt	Q01534 (UniProt - Evidence at protein level)
neXtProt	NX_Q01534
Antibodypedia	TSPY1 antibodies

PROTEIN BROWSER

TSPY1-001	TSPY1-201	TSPY1-202	TSPY1-203

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TSPY1-001 ENSP00000403304 ENST00000451548	Q01534 [Direct mapping] Testis-specific Y-encoded protein 1 Show all	Predicted intracellular proteins Disease related genes Show all	GO:0003674 [molecular_function] GO:0005515 [protein binding] GO:0005575 [cellular_component] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0006334 [nucleosome assembly] GO:0007283 [spermatogenesis] GO:0007506 [gonadal mesoderm development] GO:0007548 [sex differentiation] GO:0008283 [cell proliferation] GO:0030154 [cell differentiation] Show all	308 aa 35 kDa	No	0
TSPY1-201 ENSP00000389324 ENST00000423647	Q01534 [Direct mapping] Testis-specific Y-encoded protein 1 Show all	Predicted intracellular proteins Disease related genes Show all	GO:0003674 [molecular_function] GO:0005515 [protein binding] GO:0005575 [cellular_component] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0006334 [nucleosome assembly] GO:0007283 [spermatogenesis] GO:0007506 [gonadal mesoderm development] GO:0007548 [sex differentiation] GO:0008283 [cell proliferation] GO:0030154 [cell differentiation] Show all	294 aa 33.2 kDa	No	0
TSPY1-202 ENSP00000406010 ENST00000440483	A4FUW6 [Direct mapping] LOC728395 protein; Testis-specific Y-encoded protein 1 Show all	Predicted intracellular proteins Show all	GO:0005634 [nucleus] GO:0006334 [nucleosome assembly] Show all	221 aa 25.9 kDa	No	0
TSPY1-203 ENSP00000473286 ENST00000446779	R4GMP3 [Direct mapping] Testis-specific Y-encoded protein 1 Show all	Predicted intracellular proteins Show all	GO:0005634 [nucleus] GO:0006334 [nucleosome assembly] Show all	308 aa 35.1 kDa	No	0