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TSPY1

GENERAL INFORMATION

Gene name

 TSPY1

Gene description

 Testis specific protein, Y-linked 1

Protein class

 Disease related genes
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 4
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enriched (testis)
GTEx:Tissue enriched (testis)

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in spermatogonia.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Caution, targets protein from more than one gene. Pending external verification.

Reliability score

 Supported based on 1 antibody.
HPA049384
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (testis)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (testis)

GENE INFORMATION

Gene name

 TSPY1 (HGNC Symbol)

Synonyms

 CT78, TSPY

Description

 Testis specific protein, Y-linked 1 (HGNC Symbol)

Entrez gene summary

 The protein encoded by this gene is found only in testicular tissue and may be involved in spermatogenesis. Approximately 35 copies of this gene are present in humans, but only a single, nonfunctional orthologous gene is found in mouse. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]

Chromosome

 Y

Cytoband

 p11.2

Chromosome location (bp)

 9466955 - 9490081

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000258992 (version 83.38)

Entrez gene

 7258

UniProt

 Q01534 (UniProt - Evidence at protein level)

neXtProt

 NX_Q01534

Antibodypedia

 TSPY1 antibodies

PROTEIN BROWSER
TSPY1-001
TSPY1-201
TSPY1-202
TSPY1-203

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
TSPY1-001
ENSP00000403304
ENST00000451548
Q01534 [Direct mapping]
Testis-specific Y-encoded protein 1
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Predicted intracellular proteins
Disease related genes
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GO:0003674 [molecular_function]
GO:0005515 [protein binding]
GO:0005575 [cellular_component]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0006334 [nucleosome assembly]
GO:0007283 [spermatogenesis]
GO:0007506 [gonadal mesoderm development]
GO:0007548 [sex differentiation]
GO:0008283 [cell proliferation]
GO:0030154 [cell differentiation]
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 308 aa
35 kDa 		No 0
TSPY1-201
ENSP00000389324
ENST00000423647
Q01534 [Direct mapping]
Testis-specific Y-encoded protein 1
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Predicted intracellular proteins
Disease related genes
Show all
GO:0003674 [molecular_function]
GO:0005515 [protein binding]
GO:0005575 [cellular_component]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0006334 [nucleosome assembly]
GO:0007283 [spermatogenesis]
GO:0007506 [gonadal mesoderm development]
GO:0007548 [sex differentiation]
GO:0008283 [cell proliferation]
GO:0030154 [cell differentiation]
Show all
 294 aa
33.2 kDa 		No 0
TSPY1-202
ENSP00000406010
ENST00000440483
A4FUW6 [Direct mapping]
LOC728395 protein; Testis-specific Y-encoded protein 1
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Predicted intracellular proteins
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GO:0005634 [nucleus]
GO:0006334 [nucleosome assembly]
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 221 aa
25.9 kDa 		No 0
TSPY1-203
ENSP00000473286
ENST00000446779
R4GMP3 [Direct mapping]
Testis-specific Y-encoded protein 1
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Predicted intracellular proteins
Show all
GO:0005634 [nucleus]
GO:0006334 [nucleosome assembly]
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 308 aa
35.1 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.