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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Tissue

Detectable

Cell line

Detectable

Category

Score

Score

Score

Antibodies

Column

 
 
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ST20-MTHFS
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CANCER ATLAS

GENE/PROTEIN

Antibody validation

Dictionary

Level of antibody staining/expression





High
Medium
Low
Not detected

CANCER ATLAS

Gene description

ST20-MTHFS readthrough

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at transcript level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY

HPA008067

Tissue

Cancer staining

Breast cancer
Carcinoid
Cervical cancer
Colorectal cancer
Endometrial cancer
Glioma
Head and neck cancer
Liver cancer
Lung cancer
Lymphoma
 

Tissue

Cancer staining

Melanoma
Ovarian cancer
Pancreatic cancer
Prostate cancer
Renal cancer
Skin cancer
Stomach cancer
Testis cancer
Thyroid cancer
Urothelial cancer

Staining summary

Most cancer tissues showed moderate to strong cytoplasmic staining. A majority of gliomas and skin cancers were negative.

GENE INFORMATION

Gene name

ST20-MTHFS

Synonyms

Description

ST20-MTHFS readthrough (HGNC Symbol)

Entrez gene summary

This locus represents naturally occurring read-through transcription between the neighboring suppressor of tumorigenicity 20 and 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) genes on chromosome 15. The read-through transcript produces a fusion protein that shares sequence identity with each individual gene product. [provided by RefSeq, Dec 2010]

Chromosome

15

Cytoband

q25.1

Chromosome location (bp)

79845150 - 79923754

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000259332 (version 83.38)

Entrez gene

100528021

UniProt

neXtProt

Antibodypedia

ST20-MTHFS antibodies

PROTEIN BROWSER

ST20-MTHFS-001
ST20-MTHFS-002
ST20-MTHFS-003

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ST20-MTHFS-001
ENSP00000489298
ENST00000494999
Predicted intracellular proteins
Show all
123 aa
14.1 kDa
No 0
ST20-MTHFS-002
ENSP00000455643
ENST00000479961
A0A0A6YYL1 [Direct mapping]
5-formyltetrahydrofolate cyclo-ligase
Show all
Predicted intracellular proteins
Show all
GO:0005524 [ATP binding]
GO:0008152 [metabolic process]
GO:0030272 [5-formyltetrahydrofolate cyclo-ligase activity]
GO:0046872 [metal ion binding]
Show all
179 aa
20.5 kDa
No 0
ST20-MTHFS-003
ENSP00000489525
ENST00000615374
Predicted intracellular proteins
Show all
179 aa
20.5 kDa
No 0

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