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THTPA

CANCER ATLAS

Gene description

 Thiamine triphosphatase

Protein class

 Enzymes, Predicted intracellular proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Thyroid cancer

STAINING SUMMARY
HPA028876

GENE INFORMATION

Gene name

 THTPA (HGNC Symbol)

Synonyms

 THTPASE

Description

 Thiamine triphosphatase (HGNC Symbol)

Entrez gene summary

 This gene encodes an enzyme which catalyzes the biosynthesis of thiamine disphophate (vitamin B1) by hydrolysis of thiamine triphosphate. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011]

Chromosome

 14

Cytoband

 q11.2

Chromosome location (bp)

 23555988 - 23560271

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000259431 (version 83.38)

Entrez gene

 79178

UniProt

 Q9BU02 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9BU02

Antibodypedia

 THTPA antibodies

PROTEIN BROWSER
THTPA-001
THTPA-002
THTPA-003
THTPA-005
THTPA-007
THTPA-008
THTPA-009

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
THTPA-001
ENSP00000288014
ENST00000288014
Q9BU02 [Direct mapping]
Thiamine-triphosphatase
Show all
Enzymes
   ENZYME proteins
   Hydrolases
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000287 [magnesium ion binding]
GO:0005829 [cytosol]
GO:0006091 [generation of precursor metabolites and energy]
GO:0006766 [vitamin metabolic process]
GO:0006767 [water-soluble vitamin metabolic process]
GO:0006772 [thiamine metabolic process]
GO:0016311 [dephosphorylation]
GO:0016787 [hydrolase activity]
GO:0042357 [thiamine diphosphate metabolic process]
GO:0042723 [thiamine-containing compound metabolic process]
GO:0044281 [small molecule metabolic process]
GO:0050333 [thiamin-triphosphatase activity]
Show all
 230 aa
25.6 kDa 		No 0
THTPA-002
ENSP00000384580
ENST00000404535
Q9BU02 [Direct mapping]
Thiamine-triphosphatase
Show all
Enzymes
   ENZYME proteins
   Hydrolases
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000287 [magnesium ion binding]
GO:0005829 [cytosol]
GO:0006091 [generation of precursor metabolites and energy]
GO:0006766 [vitamin metabolic process]
GO:0006767 [water-soluble vitamin metabolic process]
GO:0006772 [thiamine metabolic process]
GO:0016311 [dephosphorylation]
GO:0016787 [hydrolase activity]
GO:0042357 [thiamine diphosphate metabolic process]
GO:0042723 [thiamine-containing compound metabolic process]
GO:0044281 [small molecule metabolic process]
GO:0050333 [thiamin-triphosphatase activity]
Show all
 230 aa
25.6 kDa 		No 0
THTPA-003
ENSP00000450459
ENST00000554789
Q9BU02 [Direct mapping]
Thiamine-triphosphatase
Show all
Enzymes
   ENZYME proteins
   Hydrolases
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000287 [magnesium ion binding]
GO:0005829 [cytosol]
GO:0006091 [generation of precursor metabolites and energy]
GO:0006766 [vitamin metabolic process]
GO:0006767 [water-soluble vitamin metabolic process]
GO:0006772 [thiamine metabolic process]
GO:0016311 [dephosphorylation]
GO:0016787 [hydrolase activity]
GO:0042357 [thiamine diphosphate metabolic process]
GO:0042723 [thiamine-containing compound metabolic process]
GO:0044281 [small molecule metabolic process]
GO:0050333 [thiamin-triphosphatase activity]
Show all
 105 aa
12 kDa 		No 0
THTPA-005
ENSP00000452164
ENST00000556545
H0YJU8 [Direct mapping]
Thiamine-triphosphatase
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 60 aa
6.7 kDa 		No 0
THTPA-007
ENSP00000451835
ENST00000556015
Q9BU02 [Direct mapping]
Thiamine-triphosphatase
Show all
Enzymes
   ENZYME proteins
   Hydrolases
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000287 [magnesium ion binding]
GO:0005829 [cytosol]
GO:0006091 [generation of precursor metabolites and energy]
GO:0006766 [vitamin metabolic process]
GO:0006767 [water-soluble vitamin metabolic process]
GO:0006772 [thiamine metabolic process]
GO:0016311 [dephosphorylation]
GO:0016787 [hydrolase activity]
GO:0042357 [thiamine diphosphate metabolic process]
GO:0042723 [thiamine-containing compound metabolic process]
GO:0044281 [small molecule metabolic process]
GO:0050333 [thiamin-triphosphatase activity]
Show all
 105 aa
12 kDa 		No 0
THTPA-008
ENSP00000452465
ENST00000554970
G3V5Q5 [Direct mapping]
Thiamine-triphosphatase
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
 140 aa
16 kDa 		No 0
THTPA-009
ENSP00000452281
ENST00000557630
G3V5B9 [Direct mapping]
Thiamine-triphosphatase
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 123 aa
13.5 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.