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Cancer cells were generally negative. A few cases of colorectal, cervical, lung and testicular cancers displayed weak to moderate nuclear positivity.
GENE INFORMATION
Gene name
RBM15B (HGNC Symbol)
Synonyms
HUMAGCGB, OTT3
Description
RNA binding motif protein 15B (HGNC Symbol)
Entrez gene summary
Members of the SPEN (Split-end) family of proteins, including RBM15B, have repressor function in several signaling pathways and may bind to RNA through interaction with spliceosome components (Hiriart et al., 2005 [PubMed 16129689]).[supplied by OMIM, Feb 2009]