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RBM15B

GENERAL INFORMATION

Gene name

 RBM15B

Gene description

 RNA binding motif protein 15B

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Nuclear expression with a granular pattern in several tissues.

DATA RELIABILITY

Data reliability
description

 Pending external verification. Cytoplasmic positivity observed and disregarded.

Reliability score

 Approved based on 1 antibody.
HPA036645
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 RBM15B (HGNC Symbol)

Synonyms

 HUMAGCGB, OTT3

Description

 RNA binding motif protein 15B (HGNC Symbol)

Entrez gene summary

 Members of the SPEN (Split-end) family of proteins, including RBM15B, have repressor function in several signaling pathways and may bind to RNA through interaction with spliceosome components (Hiriart et al., 2005 [PubMed 16129689]).[supplied by OMIM, Feb 2009]

Chromosome

 3

Cytoband

 p21.2

Chromosome location (bp)

 51391268 - 51397908

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000259956 (version 83.38)

Entrez gene

 29890

UniProt

 Q8NDT2 (UniProt - Evidence at protein level)

neXtProt

 NX_Q8NDT2

Antibodypedia

 RBM15B antibodies

PROTEIN BROWSER
RBM15B-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
RBM15B-001
ENSP00000454545
ENST00000563281
Q8NDT2 [Direct mapping]
Putative RNA-binding protein 15B
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
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GO:0000166 [nucleotide binding]
GO:0000381 [regulation of alternative mRNA splicing, via spliceosome]
GO:0003676 [nucleic acid binding]
GO:0003723 [RNA binding]
GO:0005515 [protein binding]
GO:0005654 [nucleoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006397 [mRNA processing]
GO:0008380 [RNA splicing]
GO:0016032 [viral process]
GO:0044822 [poly(A) RNA binding]
Show all
 890 aa
97.2 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.