Expression of SCRT1 in cancer - Summary

CANCER ATLAS

Gene description

Scratch family zinc finger 1

Protein class

Plasma proteins, Predicted intracellular proteins, Transcription factors

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

STAINING SUMMARY

HPA045265

GENE INFORMATION
Gene name	SCRT1 (HGNC Symbol)
Synonyms	DKFZp547F072, ZNF898
Description	Scratch family zinc finger 1 (HGNC Symbol)
Entrez gene summary	This gene encodes a C2H2-type zinc finger transcriptional repressor that binds to E-box motifs. The encoded protein may promote neural differention and may be involved in cancers with neuroendocrine features. [provided by RefSeq, Jul 2013]
Chromosome	8
Cytoband	q24.3
Chromosome location (bp)	144330565 - 144336281
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000261678 (version 83.38)
Entrez gene	83482
UniProt	Q9BWW7 (UniProt - Evidence at protein level)
neXtProt	NX_Q9BWW7
Antibodypedia	SCRT1 antibodies

PROTEIN BROWSER

SCRT1-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SCRT1-001 ENSP00000455711 ENST00000569446	Q9BWW7 [Direct mapping] Transcriptional repressor scratch 1 Show all	Predicted intracellular proteins Plasma proteins Transcription factors Zinc-coordinating DNA-binding domains Show all	GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0003677 [DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] GO:2001222 [regulation of neuron migration] Show all	348 aa 35.6 kDa	No	0