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RPL17

GENERAL INFORMATION

Gene name

 RPL17

Gene description

 Ribosomal protein L17

Protein class

 Plasma proteins
Predicted intracellular proteins
Ribosomal proteins

Predicted localization

 Intracellular

Number of transcripts

 15
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Ubiquitous cytoplasmic expression.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Caution, targets protein from more than one gene.

Reliability score

 Supported based on 2 antibodies.
HPA043724 , HPA046385
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Pancreas

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 RPL17 (HGNC Symbol)

Synonyms

 L17, rpL23

Description

 Ribosomal protein L17 (HGNC Symbol)

Entrez gene summary

 Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L22P family of ribosomal proteins. It is located in the cytoplasm. This gene has been referred to as rpL23 because the encoded protein shares amino acid identity with ribosomal protein L23 from Halobacterium marismortui; however, its official symbol is RPL17. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream C18orf32 (chromosome 18 open reading frame 32) gene. [provided by RefSeq, Dec 2010]

Chromosome

 18

Cytoband

 q21.1

Chromosome location (bp)

 49488453 - 49492523

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000265681 (version 83.38)

Entrez gene

 6139

UniProt

 P18621 (UniProt - Evidence at protein level)

neXtProt

 NX_P18621

Antibodypedia

 RPL17 antibodies

PROTEIN BROWSER
«
RPL17-001
RPL17-002
RPL17-003
RPL17-008
RPL17-010
RPL17-015
RPL17-016
RPL17-017
RPL17-018
RPL17-019
RPL17-022
RPL17-023
RPL17-024
RPL17-025
RPL17-026
»

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
RPL17-001
ENSP00000462385
ENST00000580261
P18621 [Direct mapping]
60S ribosomal protein L17
A0A024R261 [Target identity:100%; Query identity:100%]
HCG24487, isoform CRA_c
Show all
Ribosomal proteins
Predicted intracellular proteins
Plasma proteins
Show all
GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay]
GO:0002181 [cytoplasmic translation]
GO:0003735 [structural constituent of ribosome]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005829 [cytosol]
GO:0005840 [ribosome]
GO:0006412 [translation]
GO:0006413 [translational initiation]
GO:0006414 [translational elongation]
GO:0006415 [translational termination]
GO:0006614 [SRP-dependent cotranslational protein targeting to membrane]
GO:0010467 [gene expression]
GO:0015934 [large ribosomal subunit]
GO:0016032 [viral process]
GO:0019058 [viral life cycle]
GO:0019083 [viral transcription]
GO:0022625 [cytosolic large ribosomal subunit]
GO:0044267 [cellular protein metabolic process]
GO:0044822 [poly(A) RNA binding]
Show all
 184 aa
21.4 kDa 		No 0
RPL17-002
ENSP00000462944
ENST00000581373
P18621 [Direct mapping]
60S ribosomal protein L17
Show all
Ribosomal proteins
Predicted intracellular proteins
Plasma proteins
Show all
GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay]
GO:0002181 [cytoplasmic translation]
GO:0003735 [structural constituent of ribosome]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005829 [cytosol]
GO:0005840 [ribosome]
GO:0006412 [translation]
GO:0006413 [translational initiation]
GO:0006414 [translational elongation]
GO:0006415 [translational termination]
GO:0006614 [SRP-dependent cotranslational protein targeting to membrane]
GO:0010467 [gene expression]
GO:0015934 [large ribosomal subunit]
GO:0016032 [viral process]
GO:0019058 [viral life cycle]
GO:0019083 [viral transcription]
GO:0022625 [cytosolic large ribosomal subunit]
GO:0044267 [cellular protein metabolic process]
GO:0044822 [poly(A) RNA binding]
Show all
 146 aa
17.1 kDa 		No 0
RPL17-003
ENSP00000463842
ENST00000579408
P18621 [Direct mapping]
60S ribosomal protein L17
A0A024R261 [Target identity:100%; Query identity:100%]
HCG24487, isoform CRA_c
Show all
Ribosomal proteins
Predicted intracellular proteins
Plasma proteins
Show all
GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay]
GO:0002181 [cytoplasmic translation]
GO:0003735 [structural constituent of ribosome]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005829 [cytosol]
GO:0005840 [ribosome]
GO:0006412 [translation]
GO:0006413 [translational initiation]
GO:0006414 [translational elongation]
GO:0006415 [translational termination]
GO:0006614 [SRP-dependent cotranslational protein targeting to membrane]
GO:0010467 [gene expression]
GO:0015934 [large ribosomal subunit]
GO:0016032 [viral process]
GO:0019058 [viral life cycle]
GO:0019083 [viral transcription]
GO:0022625 [cytosolic large ribosomal subunit]
GO:0044267 [cellular protein metabolic process]
GO:0044822 [poly(A) RNA binding]
Show all
 184 aa
21.4 kDa 		No 0
RPL17-008
ENSP00000464586
ENST00000583036
J3QS96 [Direct mapping]
60S ribosomal protein L17
Show all
Predicted intracellular proteins
Show all
GO:0003735 [structural constituent of ribosome]
GO:0005840 [ribosome]
GO:0006412 [translation]
GO:0015934 [large ribosomal subunit]
Show all
 138 aa
16 kDa 		No 0
RPL17-010
ENSP00000462508
ENST00000578528
J3KSJ0 [Direct mapping]
60S ribosomal protein L17
Show all
Predicted intracellular proteins
Show all
GO:0003735 [structural constituent of ribosome]
GO:0005840 [ribosome]
GO:0006412 [translation]
GO:0015934 [large ribosomal subunit]
Show all
 56 aa
6.5 kDa 		No 0
RPL17-015
ENSP00000463490
ENST00000580210
J3QLC8 [Direct mapping]
60S ribosomal protein L17
Show all
Predicted intracellular proteins
Show all
GO:0003735 [structural constituent of ribosome]
GO:0005622 [intracellular]
GO:0005840 [ribosome]
GO:0006412 [translation]
GO:0015934 [large ribosomal subunit]
Show all
 174 aa
20.2 kDa 		No 0
RPL17-016
ENSP00000462203
ENST00000583637
J3KRX5 [Direct mapping]
60S ribosomal protein L17
Show all
Predicted intracellular proteins
Show all
GO:0003735 [structural constituent of ribosome]
GO:0005622 [intracellular]
GO:0005840 [ribosome]
GO:0006412 [translation]
GO:0015934 [large ribosomal subunit]
Show all
 174 aa
20.2 kDa 		No 0
RPL17-017
ENSP00000463885
ENST00000578532
J3QQT2 [Direct mapping]
60S ribosomal protein L17
Show all
Predicted intracellular proteins
Show all
GO:0003735 [structural constituent of ribosome]
GO:0005622 [intracellular]
GO:0005840 [ribosome]
GO:0006412 [translation]
GO:0015934 [large ribosomal subunit]
Show all
 171 aa
19.8 kDa 		No 0
RPL17-018
ENSP00000462023
ENST00000579248
P18621 [Direct mapping]
60S ribosomal protein L17
A0A024R261 [Target identity:100%; Query identity:100%]
HCG24487, isoform CRA_c
Show all
Ribosomal proteins
Predicted intracellular proteins
Plasma proteins
Show all
GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay]
GO:0002181 [cytoplasmic translation]
GO:0003735 [structural constituent of ribosome]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005829 [cytosol]
GO:0005840 [ribosome]
GO:0006412 [translation]
GO:0006413 [translational initiation]
GO:0006414 [translational elongation]
GO:0006415 [translational termination]
GO:0006614 [SRP-dependent cotranslational protein targeting to membrane]
GO:0010467 [gene expression]
GO:0015934 [large ribosomal subunit]
GO:0016032 [viral process]
GO:0019058 [viral life cycle]
GO:0019083 [viral transcription]
GO:0022625 [cytosolic large ribosomal subunit]
GO:0044267 [cellular protein metabolic process]
GO:0044822 [poly(A) RNA binding]
Show all
 184 aa
21.4 kDa 		No 0
RPL17-019
ENSP00000461910
ENST00000580387
J3KRB3 [Direct mapping]
60S ribosomal protein L17
Show all
Predicted intracellular proteins
Show all
GO:0003735 [structural constituent of ribosome]
GO:0005840 [ribosome]
GO:0006412 [translation]
GO:0015934 [large ribosomal subunit]
Show all
 129 aa
14.9 kDa 		No 0
RPL17-022
ENSP00000481145
ENST00000617346
A0A087WXM6 [Direct mapping]
60S ribosomal protein L17
Show all
Predicted intracellular proteins
Show all
GO:0003735 [structural constituent of ribosome]
GO:0005622 [intracellular]
GO:0005840 [ribosome]
GO:0006412 [translation]
GO:0015934 [large ribosomal subunit]
Show all
 169 aa
19.6 kDa 		No 0
RPL17-023
ENSP00000482577
ENST00000618619
P18621 [Direct mapping]
60S ribosomal protein L17
A0A024R261 [Target identity:100%; Query identity:100%]
HCG24487, isoform CRA_c
Show all
Ribosomal proteins
Predicted intracellular proteins
Plasma proteins
Show all
GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay]
GO:0002181 [cytoplasmic translation]
GO:0003735 [structural constituent of ribosome]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005829 [cytosol]
GO:0005840 [ribosome]
GO:0006412 [translation]
GO:0006413 [translational initiation]
GO:0006414 [translational elongation]
GO:0006415 [translational termination]
GO:0006614 [SRP-dependent cotranslational protein targeting to membrane]
GO:0010467 [gene expression]
GO:0015934 [large ribosomal subunit]
GO:0016032 [viral process]
GO:0019058 [viral life cycle]
GO:0019083 [viral transcription]
GO:0022625 [cytosolic large ribosomal subunit]
GO:0044267 [cellular protein metabolic process]
GO:0044822 [poly(A) RNA binding]
Show all
 184 aa
21.4 kDa 		No 0
RPL17-024
ENSP00000480215
ENST00000615760
A0A087WWH0 [Direct mapping]
60S ribosomal protein L17
Show all
Predicted intracellular proteins
Show all
GO:0003735 [structural constituent of ribosome]
GO:0005840 [ribosome]
GO:0006412 [translation]
GO:0015934 [large ribosomal subunit]
Show all
 132 aa
15.3 kDa 		No 0
RPL17-025
ENSP00000481587
ENST00000615479
A0A087WY81 [Direct mapping]
60S ribosomal protein L17
Show all
Predicted intracellular proteins
Show all
GO:0003735 [structural constituent of ribosome]
GO:0005840 [ribosome]
GO:0006412 [translation]
GO:0015934 [large ribosomal subunit]
Show all
 98 aa
11.4 kDa 		No 0
RPL17-026
ENSP00000480555
ENST00000618613
P18621 [Direct mapping]
60S ribosomal protein L17
A0A024R261 [Target identity:100%; Query identity:100%]
HCG24487, isoform CRA_c
Show all
Ribosomal proteins
Predicted intracellular proteins
Plasma proteins
Show all
GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay]
GO:0002181 [cytoplasmic translation]
GO:0003735 [structural constituent of ribosome]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005829 [cytosol]
GO:0005840 [ribosome]
GO:0006412 [translation]
GO:0006413 [translational initiation]
GO:0006414 [translational elongation]
GO:0006415 [translational termination]
GO:0006614 [SRP-dependent cotranslational protein targeting to membrane]
GO:0010467 [gene expression]
GO:0015934 [large ribosomal subunit]
GO:0016032 [viral process]
GO:0019058 [viral life cycle]
GO:0019083 [viral transcription]
GO:0022625 [cytosolic large ribosomal subunit]
GO:0044267 [cellular protein metabolic process]
GO:0044822 [poly(A) RNA binding]
Show all
 184 aa
21.4 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.