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Most cancer tissues showed moderate to strong nuclear positivity with additional cytoplasmic and/or membranous staining in several cases of ovarian, breast, pancreatic, stomach and urothelial cancers. Most of the carcinoids, renal and liver cancers were weakly stained or negative.
Cancer cells exhibited nuclear and/or cytoplasmic positivity of varying intensity. Strong nuclear staining was observed in basal cell carcinomas.
GENE INFORMATION
Gene name
CWC25 (HGNC Symbol)
Synonyms
CCDC49, FLJ20291
Description
CWC25 spliceosome-associated protein homolog (HGNC Symbol)
Entrez gene summary
This gene encodes a factor that is part of the multi-protein C complex involved in pre-mRNA splicing. Alternatively spliced transcripts have been described for this gene. [provided by RefSeq, Nov 2012]