Cell atlas - CWC25 - The Human Protein Atlas

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CWC25

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nuclear speckles

Human cell
	Nucleoplasm

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GENERAL INFORMATION
Gene name	CWC25
Gene description	CWC25 spliceosome-associated protein homolog
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the nuclear speckles.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Nuclear speckles (validated)

DATA RELIABILITY
Reliability score	Validated based on 2 antibodies. CAB014874 , HPA062997
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ASSAYS

RNA expression

Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the nuclear speckles.

Main location

Nuclear speckles (validated)


	Toggle channels	Low High G1 S G2 M N/A

Antibody	Cell line	Location
CAB014874	A-431	Nuclear speckles
CAB014874	U-2 OS	Nuclear speckles
CAB014874	U-251 MG	Nuclear speckles
HPA062997	HEK 293	Nuclear speckles
HPA062997	U-2 OS	Nuclear speckles
HPA062997	U-251 MG	Nuclear speckles

GENE INFORMATION
Gene name	CWC25 (HGNC Symbol)
Synonyms	CCDC49, FLJ20291
Description	CWC25 spliceosome-associated protein homolog (HGNC Symbol)
Entrez gene summary	This gene encodes a factor that is part of the multi-protein C complex involved in pre-mRNA splicing. Alternatively spliced transcripts have been described for this gene. [provided by RefSeq, Nov 2012]
Chromosome	17
Cytoband	q12
Chromosome location (bp)	38800434 - 38825481
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000273559 (version 83.38)
Entrez gene	54883
UniProt	Q9NXE8 (UniProt - Evidence at protein level)
neXtProt	NX_Q9NXE8
Antibodypedia	CWC25 antibodies

PROTEIN BROWSER

CWC25-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CWC25-001 ENSP00000478070 ENST00000614790	Q9NXE8 [Direct mapping] Pre-mRNA-splicing factor CWC25 homolog Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all		425 aa 49.6 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.