Cell atlas - ADRA2B - The Human Protein Atlas

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ADRA2B

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	ADRA2B
Gene description	Adrenoceptor alpha 2B
Protein class	Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enhanced (BEWO)
Protein evidence	Evidence at transcript level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (BEWO) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	ADRA2B (HGNC Symbol)
Synonyms	ADRA2L1, ADRA2RL1, ADRARL1
Description	Adrenoceptor alpha 2B (HGNC Symbol)
Entrez gene summary	This intronless gene encodes a seven-pass transmembrane protein. This protein is a member of a subfamily of G protein-coupled receptors that regulate neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. [provided by RefSeq, Apr 2014]
Chromosome	2
Cytoband	q11.2
Chromosome location (bp)	96112875 - 96116245
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000274286 (version 83.38)
Entrez gene	151
UniProt
neXtProt
Antibodypedia	ADRA2B antibodies

PROTEIN BROWSER

ADRA2B-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ADRA2B-001 ENSP00000480573 ENST00000620793	A2RUS0 [Direct mapping] Adrenergic, alpha-2B-, receptor; Alpha-2B adrenergic receptor; HCG37297 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Show all	GO:0000165 [MAPK cascade] GO:0000187 [activation of MAPK activity] GO:0001525 [angiogenesis] GO:0003056 [regulation of vascular smooth muscle contraction] GO:0004930 [G-protein coupled receptor activity] GO:0004935 [adrenergic receptor activity] GO:0004938 [alpha2-adrenergic receptor activity] GO:0005622 [intracellular] GO:0005886 [plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007565 [female pregnancy] GO:0016021 [integral component of membrane] GO:0030168 [platelet activation] GO:0045777 [positive regulation of blood pressure] GO:0070474 [positive regulation of uterine smooth muscle contraction] GO:0071875 [adrenergic receptor signaling pathway] Show all	450 aa 50 kDa	No	7

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.