THE HUMAN PROTEIN ATLAS BLOG

Invited lecture at the 29th European Congress of Pathology

2017-08-30
Conference Diagnostics Human Protein Atlas Life Science Pathology Pathology Atlas

This weekend Amsterdam is hosting the 29th European Congress of Pathology (ECP 2017). Fredrik Ponten, Co-Founder and Clinical Director of the Human Protein Atlas program, will present a lecture on September 3 entitled "Tissue-based map of the human proteome as tool for pathology". The focus of this year´s European congress will be "Pathology for Patient Care" highlighting the added value of the pathology science and discipline in providing care and improving health outcomes for patients and population. The congress is expected to provide updates on all aspects of diagnostic and molecular pathology...Read more


Highlighting the prognostic genes in colon cancer

2017-08-25
Cancer Colorectal cancer Immunohistochemistry Pathology Atlas

Figure 1. Immunohistochemical staining of JDP2 protein using HPA059511 antibody shows a differential expression in samples from colorectal cancer patients.

Last week the Human Protein Atlas portal was updated with a new Pathology Atlas - an interactive atlas where the expression of specific genes and their influence on patient survival in the 17 major cancer types can be explored. The Pathology Atlas includes quantitative genome-wide transcriptomics data (RNA-seq) of the 17 cancers coupled with clinical outcome and spatial proteomics data (immunohistochemistry) of more than 15,000 proteins.

During the next weeks, we will highlight different cancer types included in the analysis and also show examples of genes with unfavourable and favourable prognostic significance. This week's news article features colorectal cancer...Read more


New Pathology Atlas maps the genes involved in cancer and promotes personalized cancer medicine

2017-08-17
Cancer Human Protein Atlas Pathology Atlas

Pathology Atlas principle

A new Pathology Atlas is launched today with an analysis of all human genes in all major cancers showing the consequence of their corresponding protein levels for overall patient survival. The difference in expression patterns of individual cancers observed in the study strongly reinforces the need for personalized cancer treatment based on precision medicine. In addition, the systems level approach used to construct the Pathology Atlas demonstrates the power of "big data" to change how medical research is performed.

The dream of personalized treatment for cancer patients takes a major step forward today with the launch by Swedish researchers of the Human Pathology Atlas...Read more


The Human Protein Atlas selected as European core resource in life science by ELIXIR

2017-08-09
Human Protein Atlas Precision medicine

ELIXIR is an intergovernmental organisation that brings together life science resources from across Europe. These resources include databases, software tools, training materials, cloud storage and supercomputers. The goal of ELIXIR is to coordinate these resources so that they form a single infrastructure. This infrastructure makes it easier for scientists to find and share data, exchange expertise, and agree on best practices. Ultimately, it will help them gain new insights into how living organisms work.

On July 25, 2017, ELIXIR announced the selected list of ELIXIR Core Data Resources...Read more


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