THE HUMAN PROTEIN ATLAS BLOG

Focusing on prognostic genes in breast cancer

2017-09-07
Breast Cancer Cancer Cancer Genome Atlas Immunohistochemistry Pathology Atlas TCGA tissue

Figure 1. Immunohistochemical staining of CBX3 using antibody HPA004902 shows a differential nuclear expression in samples from breast cancer patients.

The Pathology Atlas, recently published in Science presents key proteins associated with different cancer types. This week's news article will focus on breast cancer and proteins related to cancer prognosis.

Breast cancer is the most common invasive cancer form in women worldwide. The cancer can roughly be classified as ductal or lobular breast cancer depending on the origin. The majority of breast cancers develop sporadically, but for 5-10% of patients there is an inherited factor associated with increased breast cancer risk, namely the BRCA1 and BRCA2 genes. Women with abnormal BRCA1 or BRCA2 have higher risk of developing breast cancer...Read more


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