Expression of SARS in cancer - Summary - The Human Protein Atlas

CANCER ATLAS

Gene description

Seryl-tRNA synthetase

Protein class

Enzymes, Plasma proteins, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Testis cancer

STAINING SUMMARY

HPA016939

GENE INFORMATION
Gene name	SARS (HGNC Symbol)
Synonyms	SERS
Description	Seryl-tRNA synthetase (HGNC Symbol)
Entrez gene summary	This gene belongs to the class II amino-acyl tRNA family. The encoded enzyme catalyzes the transfer of L-serine to tRNA (Ser) and is related to bacterial and yeast counterparts. Multiple alternatively spliced transcript variants have been described but the biological validity of all variants is unknown. [provided by RefSeq, Jul 2010]
Chromosome	1
Cytoband	p13.3
Chromosome location (bp)	109213918 - 109238169
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000031698 (version 83.38)
Entrez gene	6301
UniProt	P49591 (UniProt - Evidence at protein level)
neXtProt	NX_P49591
Antibodypedia	SARS antibodies

PROTEIN BROWSER

SARS-001	SARS-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SARS-001 ENSP00000234677 ENST00000234677	P49591 [Direct mapping] Serine--tRNA ligase, cytoplasmic Show all	Enzymes ENZYME proteins Ligase Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0003723 [RNA binding] GO:0004812 [aminoacyl-tRNA ligase activity] GO:0004828 [serine-tRNA ligase activity] GO:0005524 [ATP binding] GO:0005737 [cytoplasm] GO:0005739 [mitochondrion] GO:0005829 [cytosol] GO:0006412 [translation] GO:0006418 [tRNA aminoacylation for protein translation] GO:0006434 [seryl-tRNA aminoacylation] GO:0008033 [tRNA processing] GO:0010467 [gene expression] GO:0070062 [extracellular exosome] GO:0097056 [selenocysteinyl-tRNA(Sec) biosynthetic process] Show all	514 aa 58.8 kDa	No	0
SARS-004 ENSP00000358939 ENST00000369923	Q5T5C7 [Direct mapping] Serine--tRNA ligase, cytoplasmic Show all	SCAMPI predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0004812 [aminoacyl-tRNA ligase activity] GO:0004828 [serine-tRNA ligase activity] GO:0005524 [ATP binding] GO:0005737 [cytoplasm] GO:0006418 [tRNA aminoacylation for protein translation] GO:0006434 [seryl-tRNA aminoacylation] Show all	536 aa 61.3 kDa	No	0