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Cytoplasmic and membranous expression mainly in glandular cells of gastrointestinal tract, breast, salivary gland, prostate, cells in renal tubules and urothelial cells.
Members of the Rab protein family, including RAB27B, are prenylated, membrane-bound proteins involved in vesicular fusion and trafficking (Chen et al., 1997 [PubMed 9066979]).[supplied by OMIM, Nov 2010]