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GYG2

GENERAL INFORMATION

Gene name

 GYG2

Gene description

 Glycogenin 2

Protein class

 Enzymes
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 5
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enriched (adipose tissue)
GTEx:Tissue enhanced (adipose tissue, breast)
FANTOM5:Tissue enhanced (adipose tissue, breast)

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression most abundant in liver and adipocytes.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Approved based on 2 antibodies.
HPA005495 , HPA064686
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Soft tissue

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (adipose tissue)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (adipose tissue, breast)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (adipose tissue, breast)

GENE INFORMATION

Gene name

 GYG2 (HGNC Symbol)

Synonyms

 GN-2

Description

 Glycogenin 2 (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the the glycogenin family. Glycogenin is a self-glucosylating protein involved in the initiation reactions of glycogen biosynthesis. A gene on chromosome 3 encodes the muscle glycogenin and this X-linked gene encodes the glycogenin mainly present in liver; both are involved in blood glucose homeostasis. This gene has a short version on chromosome Y, which is 3' truncated and can not make a functional protein. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, May 2010]

Chromosome

 X

Cytoband

 p22.33

Chromosome location (bp)

 2828788 - 2882818

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000056998 (version 83.38)

Entrez gene

 8908

UniProt

 O15488 (UniProt - Evidence at protein level)

neXtProt

 NX_O15488

Antibodypedia

 GYG2 antibodies

PROTEIN BROWSER
GYG2-001
GYG2-005
GYG2-007
GYG2-008
GYG2-010

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
GYG2-001
ENSP00000370555
ENST00000381163
O15488 [Direct mapping]
Glycogenin-2
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Enzymes
   ENZYME proteins
   Transferases
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005829 [cytosol]
GO:0005975 [carbohydrate metabolic process]
GO:0005978 [glycogen biosynthetic process]
GO:0005980 [glycogen catabolic process]
GO:0006006 [glucose metabolic process]
GO:0008466 [glycogenin glucosyltransferase activity]
GO:0016757 [transferase activity, transferring glycosyl groups]
GO:0043202 [lysosomal lumen]
GO:0044281 [small molecule metabolic process]
Show all
 501 aa
55.2 kDa 		No 0
GYG2-005
ENSP00000487294
ENST00000353656
O15488 [Direct mapping]
Glycogenin-2
Show all
Enzymes
   ENZYME proteins
   Transferases
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005829 [cytosol]
GO:0005975 [carbohydrate metabolic process]
GO:0005978 [glycogen biosynthetic process]
GO:0005980 [glycogen catabolic process]
GO:0006006 [glucose metabolic process]
GO:0008466 [glycogenin glucosyltransferase activity]
GO:0016757 [transferase activity, transferring glycosyl groups]
GO:0043202 [lysosomal lumen]
GO:0044281 [small molecule metabolic process]
Show all
 430 aa
47.5 kDa 		No 0
GYG2-007
ENSP00000381786
ENST00000398806
O15488 [Direct mapping]
Glycogenin-2
Show all
Enzymes
   ENZYME proteins
   Transferases
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005829 [cytosol]
GO:0005975 [carbohydrate metabolic process]
GO:0005978 [glycogen biosynthetic process]
GO:0005980 [glycogen catabolic process]
GO:0006006 [glucose metabolic process]
GO:0008466 [glycogenin glucosyltransferase activity]
GO:0016757 [transferase activity, transferring glycosyl groups]
GO:0043202 [lysosomal lumen]
GO:0044281 [small molecule metabolic process]
Show all
 470 aa
52 kDa 		No 0
GYG2-008
ENSP00000430764
ENST00000520904
E5RIC9 [Direct mapping]
Glycogenin-2
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0008152 [metabolic process]
GO:0016757 [transferase activity, transferring glycosyl groups]
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 138 aa
15.5 kDa 		No 0
GYG2-010
ENSP00000370549
ENST00000381157
J3QSZ3 [Direct mapping]
Glycogenin-2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0008152 [metabolic process]
GO:0016757 [transferase activity, transferring glycosyl groups]
Show all
 244 aa
26.2 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.