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RNA tissue category: Group enriched (placenta, kidney)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (placenta)
GENE INFORMATION
Gene name
ZFAT (HGNC Symbol)
Synonyms
KIAA1485, ZFAT1, ZNF406
Description
Zinc finger and AT hook domain containing (HGNC Symbol)
Entrez gene summary
This gene encodes a protein that likely binds DNA and functions as a transcriptional regulator involved in apoptosis and cell survival. This gene resides in a susceptibility locus for autoimmune thyroid disease (AITD) on chromosome 8q24. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Nov 2009]
Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding] GO:0001077 [transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding] GO:0002244 [hematopoietic progenitor cell differentiation] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005654 [nucleoplasm] GO:0005829 [cytosol] GO:0006366 [transcription from RNA polymerase II promoter] GO:0007275 [multicellular organismal development] GO:0030097 [hemopoiesis] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0046872 [metal ion binding] GO:0060712 [spongiotrophoblast layer development]
Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005654 [nucleoplasm] GO:0005829 [cytosol] GO:0007275 [multicellular organismal development] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0046872 [metal ion binding]
Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005654 [nucleoplasm] GO:0005829 [cytosol] GO:0007275 [multicellular organismal development] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0046872 [metal ion binding]
Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005654 [nucleoplasm] GO:0005829 [cytosol] GO:0007275 [multicellular organismal development] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0046872 [metal ion binding]
