Expression of CRMP1 in cancer - Summary

CANCER ATLAS

Gene description

Collapsin response mediator protein 1

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA035640	CAB037313

GENE INFORMATION
Gene name	CRMP1 (HGNC Symbol)
Synonyms	DPYSL1, DRP-1
Description	Collapsin response mediator protein 1 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of a family of cytosolic phosphoproteins expressed exclusively in the nervous system. The encoded protein is thought to be a part of the semaphorin signal transduction pathway implicated in semaphorin-induced growth cone collapse during neural development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
Chromosome	4
Cytoband	p16.2
Chromosome location (bp)	5748084 - 5893058
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000072832 (version 83.38)
Entrez gene	1400
UniProt	Q14194 (UniProt - Evidence at protein level)
neXtProt	NX_Q14194
Antibodypedia	CRMP1 antibodies

PROTEIN BROWSER

CRMP1-001	CRMP1-002	CRMP1-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CRMP1-001 ENSP00000321606 ENST00000324989	Q14194 [Direct mapping] Dihydropyrimidinase-related protein 1 X5DNI1 [Target identity:100%; Query identity:100%] Collapsin response mediator protein 1 isoform A Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000226 [microtubule cytoskeleton organization] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005815 [microtubule organizing center] GO:0005819 [spindle] GO:0005829 [cytosol] GO:0006139 [nucleobase-containing compound metabolic process] GO:0007399 [nervous system development] GO:0007411 [axon guidance] GO:0016787 [hydrolase activity] GO:0016810 [hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds] GO:0030425 [dendrite] GO:0043025 [neuronal cell body] GO:0048666 [neuron development] Show all	686 aa 74.3 kDa	No	0
CRMP1-002 ENSP00000425742 ENST00000512574	E9PD68 [Direct mapping] Dihydropyrimidinase-related protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000226 [microtubule cytoskeleton organization] GO:0005737 [cytoplasm] GO:0007411 [axon guidance] GO:0008152 [metabolic process] GO:0016787 [hydrolase activity] GO:0016810 [hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds] Show all	570 aa 62 kDa	No	0
CRMP1-003 ENSP00000380987 ENST00000397890	Q14194 [Direct mapping] Dihydropyrimidinase-related protein 1 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000226 [microtubule cytoskeleton organization] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005815 [microtubule organizing center] GO:0005819 [spindle] GO:0005829 [cytosol] GO:0006139 [nucleobase-containing compound metabolic process] GO:0007399 [nervous system development] GO:0007411 [axon guidance] GO:0016787 [hydrolase activity] GO:0016810 [hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds] Show all	572 aa 62.2 kDa	No	0