Cell atlas - RGS11 - The Human Protein Atlas

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RGS11

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	RGS11
Gene description	Regulator of G-protein signaling 11
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enhanced (SCLC-21H, SH-SY5Y, T-47d)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (SCLC-21H, SH-SY5Y, T-47d) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	RGS11
Synonyms
Description	Regulator of G-protein signaling 11 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene belongs to the RGS (regulator of G protein signaling) family. Members of the RGS family act as GTPase-activating proteins on the alpha subunits of heterotrimeric, signal-transducing G proteins. This protein inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Alternative splicing occurs at this locus and four transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Nov 2013]
Chromosome	16
Cytoband	p13.3
Chromosome location (bp)	268301 - 275980
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000076344 (version 83.38)
Entrez gene	8786
UniProt	O94810 (UniProt - Evidence at protein level)
neXtProt	NX_O94810
Antibodypedia	RGS11 antibodies

PROTEIN BROWSER

RGS11-001	RGS11-003	RGS11-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RGS11-001 ENSP00000380876 ENST00000397770	O94810 [Direct mapping] Regulator of G-protein signaling 11 Q4TT70 [Target identity:100%; Query identity:100%] Regulator of G-protein signaling 11; Regulator of G-protein signalling 11; Regulator of G-protein signalling 11, isoform CRA_e Show all	Predicted intracellular proteins Show all	GO:0004871 [signal transducer activity] GO:0005096 [GTPase activator activity] GO:0005737 [cytoplasm] GO:0005834 [heterotrimeric G-protein complex] GO:0005886 [plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0008277 [regulation of G-protein coupled receptor protein signaling pathway] GO:0009968 [negative regulation of signal transduction] GO:0031681 [G-protein beta-subunit binding] GO:0035556 [intracellular signal transduction] GO:0043234 [protein complex] GO:0043547 [positive regulation of GTPase activity] GO:0044292 [dendrite terminus] Show all	467 aa 52.9 kDa	No	0
RGS11-003 ENSP00000319069 ENST00000316163	O94810 [Direct mapping] Regulator of G-protein signaling 11 Show all	Predicted intracellular proteins Show all	GO:0004871 [signal transducer activity] GO:0005096 [GTPase activator activity] GO:0005737 [cytoplasm] GO:0005834 [heterotrimeric G-protein complex] GO:0005886 [plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0008277 [regulation of G-protein coupled receptor protein signaling pathway] GO:0009968 [negative regulation of signal transduction] GO:0031681 [G-protein beta-subunit binding] GO:0035556 [intracellular signal transduction] GO:0043234 [protein complex] GO:0043547 [positive regulation of GTPase activity] Show all	446 aa 50.7 kDa	No	0
RGS11-004 ENSP00000352778 ENST00000359740	O94810 [Direct mapping] Regulator of G-protein signaling 11 Show all	Predicted intracellular proteins Show all	GO:0004871 [signal transducer activity] GO:0005096 [GTPase activator activity] GO:0005737 [cytoplasm] GO:0005834 [heterotrimeric G-protein complex] GO:0005886 [plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0008277 [regulation of G-protein coupled receptor protein signaling pathway] GO:0009968 [negative regulation of signal transduction] GO:0031681 [G-protein beta-subunit binding] GO:0035556 [intracellular signal transduction] GO:0043234 [protein complex] GO:0043547 [positive regulation of GTPase activity] Show all	456 aa 51.5 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.