Expression of SDF4 in cancer - Summary - The Human Protein Atlas

CANCER ATLAS

Gene description

Stromal cell derived factor 4

Protein class

Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA011249	CAB015227

GENE INFORMATION
Gene name	SDF4 (HGNC Symbol)
Synonyms	Cab45
Description	Stromal cell derived factor 4 (HGNC Symbol)
Entrez gene summary	This gene encodes a stromal cell derived factor that is a member of the CREC protein family. The encoded protein contains six EF-hand motifs and calcium-binding motifs. This protein localizes to the Golgi lumen and may be involved in regulating calcium dependent cellular activities. [provided by RefSeq, Sep 2011]
Chromosome	1
Cytoband	p36.33
Chromosome location (bp)	1216908 - 1232031
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000078808 (version 83.38)
Entrez gene	51150
UniProt	Q9BRK5 (UniProt - Evidence at protein level)
neXtProt	NX_Q9BRK5
Antibodypedia	SDF4 antibodies

PROTEIN BROWSER

SDF4-001	SDF4-006	SDF4-007

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SDF4-001 ENSP00000353094 ENST00000360001	Q9BRK5 [Direct mapping] 45 kDa calcium-binding protein A0A024R084 [Target identity:100%; Query identity:100%] Stromal cell derived factor 4, isoform CRA_c Show all	MEMSAT3 predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005509 [calcium ion binding] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005770 [late endosome] GO:0005794 [Golgi apparatus] GO:0005796 [Golgi lumen] GO:0005886 [plasma membrane] GO:0009650 [UV protection] GO:0016020 [membrane] GO:0017156 [calcium ion-dependent exocytosis] GO:0021549 [cerebellum development] GO:0032059 [bleb] GO:0042802 [identical protein binding] GO:0045444 [fat cell differentiation] GO:0045471 [response to ethanol] GO:0070062 [extracellular exosome] GO:0070625 [zymogen granule exocytosis] Show all	362 aa 41.8 kDa	Yes	0
SDF4-006 ENSP00000384207 ENST00000403997	H0Y3T6 [Direct mapping] 45 kDa calcium-binding protein Show all	SCAMPI predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005509 [calcium ion binding] Show all	243 aa 28 kDa	No	0
SDF4-007 ENSP00000263741 ENST00000263741	Q9BRK5 [Direct mapping] 45 kDa calcium-binding protein A0A024R0A9 [Target identity:100%; Query identity:100%] Stromal cell derived factor 4, isoform CRA_b Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005509 [calcium ion binding] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005770 [late endosome] GO:0005794 [Golgi apparatus] GO:0005796 [Golgi lumen] GO:0005886 [plasma membrane] GO:0009650 [UV protection] GO:0016020 [membrane] GO:0017156 [calcium ion-dependent exocytosis] GO:0021549 [cerebellum development] GO:0032059 [bleb] GO:0042802 [identical protein binding] GO:0045444 [fat cell differentiation] GO:0045471 [response to ethanol] GO:0070062 [extracellular exosome] GO:0070625 [zymogen granule exocytosis] Show all	348 aa 39.6 kDa	Yes	0