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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Tissue

Detectable

Cell line

Detectable

Category

Score

Score

Score

Antibodies

Column

 
 
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RAB10
  • TISSUE

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TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation


Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

RAB10

Gene description

RAB10, member RAS oncogene family

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

1
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Ubiquitous cytoplasmic expression.

DATA RELIABILITY

Data reliability
description

Antibody staining mainly consistent with RNA expression data.

Reliability score

Approved based on 1 antibody.
HPA045611
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
Cerebral cortex
Hippocampus
N/A
Caudate
N/A
Cerebellum
N/A
Endocrine tissues
Thyroid gland
Parathyroid gland
Adrenal gland
Bone marrow & immune system
Appendix
Bone marrow
Lymph node
Tonsil
Spleen
Muscle tissues
Heart muscle
Skeletal muscle
Smooth muscle
Lung
Nasopharynx
N/A
Bronchus
N/A
Lung
Liver & gallbladder
Liver
Gallbladder
Pancreas
Pancreas
Gastrointestinal tract
Oral mucosa
N/A
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Colon
Rectum
Kidney & urinary bladder
Kidney
Urinary bladder
Male tissues
Testis
Epididymis
Prostate
Seminal vesicle
Female tissues
Breast
Vagina
N/A
Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Adipose & soft tissue
Adipose tissue
Soft tissue
N/A
Skin
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW

Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

RAB10

Synonyms

Description

RAB10, member RAS oncogene family (HGNC Symbol)

Entrez gene summary

RAB10 belongs to the RAS (see HRAS; MIM 190020) superfamily of small GTPases. RAB proteins localize to exocytic and endocytic compartments and regulate intracellular vesicle trafficking (Bao et al., 1998 [PubMed 9918381]).[supplied by OMIM, Mar 2009]

Chromosome

2

Cytoband

p23.3

Chromosome location (bp)

26034107 - 26137454

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000084733 (version 83.38)

Entrez gene

10890

UniProt

P61026 (UniProt - Evidence at protein level)

neXtProt

NX_P61026

Antibodypedia

RAB10 antibodies

PROTEIN BROWSER

RAB10-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

RAB10-001
ENSP00000264710
ENST00000264710
P61026 [Direct mapping]
Ras-related protein Rab-10
Show all
   Phobius predicted secreted proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000145 [exocyst]
GO:0003924 [GTPase activity]
GO:0005515 [protein binding]
GO:0005525 [GTP binding]
GO:0005622 [intracellular]
GO:0005768 [endosome]
GO:0005789 [endoplasmic reticulum membrane]
GO:0005794 [Golgi apparatus]
GO:0005802 [trans-Golgi network]
GO:0005886 [plasma membrane]
GO:0005925 [focal adhesion]
GO:0006886 [intracellular protein transport]
GO:0006893 [Golgi to plasma membrane transport]
GO:0006904 [vesicle docking involved in exocytosis]
GO:0006913 [nucleocytoplasmic transport]
GO:0007165 [signal transduction]
GO:0007264 [small GTPase mediated signal transduction]
GO:0007409 [axonogenesis]
GO:0009306 [protein secretion]
GO:0010008 [endosome membrane]
GO:0015031 [protein transport]
GO:0016020 [membrane]
GO:0016192 [vesicle-mediated transport]
GO:0016197 [endosomal transport]
GO:0017157 [regulation of exocytosis]
GO:0019003 [GDP binding]
GO:0019882 [antigen processing and presentation]
GO:0030659 [cytoplasmic vesicle membrane]
GO:0030670 [phagocytic vesicle membrane]
GO:0030859 [polarized epithelial cell differentiation]
GO:0031489 [myosin V binding]
GO:0032482 [Rab protein signal transduction]
GO:0032593 [insulin-responsive compartment]
GO:0032869 [cellular response to insulin stimulus]
GO:0043001 [Golgi to plasma membrane protein transport]
GO:0045200 [establishment of neuroblast polarity]
GO:0048471 [perinuclear region of cytoplasm]
GO:0055037 [recycling endosome]
GO:0055038 [recycling endosome membrane]
GO:0061024 [membrane organization]
GO:0061467 [basolateral protein localization]
GO:0070062 [extracellular exosome]
GO:0071236 [cellular response to antibiotic]
GO:0071782 [endoplasmic reticulum tubular network]
GO:0071786 [endoplasmic reticulum tubular network organization]
GO:0072372 [primary cilium]
GO:0072659 [protein localization to plasma membrane]
GO:0090150 [establishment of protein localization to membrane]
GO:0097051 [establishment of protein localization to endoplasmic reticulum membrane]
Show all
200 aa
22.5 kDa
No 0

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