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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Tissue

Detectable

Cell line

Detectable

Category

Score

Score

Score

Antibodies

Column

 
 
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SLC25A24
  • premium

    TISSUE

  • premium

    CELL

  • CANCER

CANCER ATLAS

GENE/PROTEIN

Antibody validation

Dictionary

Level of antibody staining/expression





High
Medium
Low
Not detected

CANCER ATLAS

Gene description

Solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24

Protein class

Predicted intracellular proteins, Transporters

Protein evidence

Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY

HPA063636

Tissue

Cancer staining

Protein
expression of
normal tissue

Breast cancer
 
Carcinoid
 
Cervical cancer
 
Colorectal cancer
 
 
Endometrial cancer
 
 
Glioma
 
Head and neck cancer
 
 
Liver cancer
 
 
Lung cancer
 
 
Lymphoma
 
 
 

Tissue

Cancer staining

Protein
expression of
normal tissue

Melanoma
 
Ovarian cancer
 
Pancreatic cancer
 
Prostate cancer
 
Renal cancer
 
Skin cancer
 
Stomach cancer
 
 
Testis cancer
 
Thyroid cancer
 
Urothelial cancer
 

Staining summary

Most cancer tissues showed moderate to strong cytoplasmic positivity with a granular pattern. Gliomas and hepatocellular carcinoma were negative.

GENE INFORMATION

Gene name

SLC25A24 (HGNC Symbol)

Synonyms

APC1, DKFZp586G0123

Description

Solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 (HGNC Symbol)

Entrez gene summary

This gene encodes a carrier protein that transports ATP-Mg exchanging it for phosphate. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]

Chromosome

1

Cytoband

p13.3

Chromosome location (bp)

108134036 - 108200849

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000085491 (version 83.38)

Entrez gene

29957

UniProt

Q6NUK1 (UniProt - Evidence at protein level)

neXtProt

NX_Q6NUK1

Antibodypedia

SLC25A24 antibodies

PROTEIN BROWSER

SLC25A24-001
SLC25A24-002
SLC25A24-004

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SLC25A24-001
ENSP00000457733
ENST00000565488
Q6NUK1 [Direct mapping]
Calcium-binding mitochondrial carrier protein SCaMC-1
Show all
Transporters
   Electrochemical Potential-driven transporters
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005347 [ATP transmembrane transporter activity]
GO:0005509 [calcium ion binding]
GO:0005737 [cytoplasm]
GO:0005739 [mitochondrion]
GO:0005743 [mitochondrial inner membrane]
GO:0006839 [mitochondrial transport]
GO:0010941 [regulation of cell death]
GO:0015867 [ATP transport]
GO:0016021 [integral component of membrane]
GO:0034599 [cellular response to oxidative stress]
GO:0055085 [transmembrane transport]
GO:0071277 [cellular response to calcium ion]
Show all
477 aa
53.4 kDa
No 0
SLC25A24-002
ENSP00000359058
ENST00000370041
Q6NUK1 [Direct mapping]
Calcium-binding mitochondrial carrier protein SCaMC-1
Show all
Transporters
   Electrochemical Potential-driven transporters
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005347 [ATP transmembrane transporter activity]
GO:0005509 [calcium ion binding]
GO:0005737 [cytoplasm]
GO:0005739 [mitochondrion]
GO:0005743 [mitochondrial inner membrane]
GO:0006839 [mitochondrial transport]
GO:0010941 [regulation of cell death]
GO:0015867 [ATP transport]
GO:0016021 [integral component of membrane]
GO:0034599 [cellular response to oxidative stress]
GO:0055085 [transmembrane transport]
GO:0071277 [cellular response to calcium ion]
Show all
458 aa
51.4 kDa
No 0
SLC25A24-004
ENSP00000454393
ENST00000569674
H3BMI3 [Direct mapping]
Calcium-binding mitochondrial carrier protein SCaMC-1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005509 [calcium ion binding]
Show all
69 aa
7.7 kDa
No 0

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