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SLC25A24

GENERAL INFORMATION

Gene name

 SLC25A24

Gene description

 Solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24

Protein class

 Predicted intracellular proteins
Transporters

Predicted localization

 Intracellular

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Mixed
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 General cytoplasmic positivity with a granular mitochondrial pattern.

DATA RELIABILITY

Data reliability
description

 Antibody staining consistent with RNA expression data.

Reliability score

 Supported based on 1 antibody.
HPA063636
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 SLC25A24 (HGNC Symbol)

Synonyms

 APC1, DKFZp586G0123

Description

 Solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 (HGNC Symbol)

Entrez gene summary

 This gene encodes a carrier protein that transports ATP-Mg exchanging it for phosphate. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]

Chromosome

 1

Cytoband

 p13.3

Chromosome location (bp)

 108134036 - 108200849

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000085491 (version 83.38)

Entrez gene

 29957

UniProt

 Q6NUK1 (UniProt - Evidence at protein level)

neXtProt

 NX_Q6NUK1

Antibodypedia

 SLC25A24 antibodies

PROTEIN BROWSER
SLC25A24-001
SLC25A24-002
SLC25A24-004

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
SLC25A24-001
ENSP00000457733
ENST00000565488
Q6NUK1 [Direct mapping]
Calcium-binding mitochondrial carrier protein SCaMC-1
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Transporters
   Electrochemical Potential-driven transporters
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005347 [ATP transmembrane transporter activity]
GO:0005509 [calcium ion binding]
GO:0005737 [cytoplasm]
GO:0005739 [mitochondrion]
GO:0005743 [mitochondrial inner membrane]
GO:0006839 [mitochondrial transport]
GO:0010941 [regulation of cell death]
GO:0015867 [ATP transport]
GO:0016021 [integral component of membrane]
GO:0034599 [cellular response to oxidative stress]
GO:0055085 [transmembrane transport]
GO:0071277 [cellular response to calcium ion]
Show all
 477 aa
53.4 kDa 		No 0
SLC25A24-002
ENSP00000359058
ENST00000370041
Q6NUK1 [Direct mapping]
Calcium-binding mitochondrial carrier protein SCaMC-1
Show all
Transporters
   Electrochemical Potential-driven transporters
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005347 [ATP transmembrane transporter activity]
GO:0005509 [calcium ion binding]
GO:0005737 [cytoplasm]
GO:0005739 [mitochondrion]
GO:0005743 [mitochondrial inner membrane]
GO:0006839 [mitochondrial transport]
GO:0010941 [regulation of cell death]
GO:0015867 [ATP transport]
GO:0016021 [integral component of membrane]
GO:0034599 [cellular response to oxidative stress]
GO:0055085 [transmembrane transport]
GO:0071277 [cellular response to calcium ion]
Show all
 458 aa
51.4 kDa 		No 0
SLC25A24-004
ENSP00000454393
ENST00000569674
H3BMI3 [Direct mapping]
Calcium-binding mitochondrial carrier protein SCaMC-1
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005509 [calcium ion binding]
Show all
 69 aa
7.7 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.