Expression of SALL4 in cancer - Summary

CANCER ATLAS

Gene description

Spalt-like transcription factor 4

Protein class

Disease related genes, Predicted intracellular proteins, Transcription factors

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA015291	HPA015791

GENE INFORMATION
Gene name	SALL4 (HGNC Symbol)
Synonyms	dJ1112F19.1, ZNF797
Description	Spalt-like transcription factor 4 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene may be a zinc finger transcription factor. Defects in this gene are a cause of Duane-radial ray syndrome (DRRS). [provided by RefSeq, Jul 2008]
Chromosome	20
Cytoband	q13.2
Chromosome location (bp)	51782331 - 51802520
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000101115 (version 83.38)
Entrez gene	57167
UniProt	Q9UJQ4 (UniProt - Evidence at protein level)
neXtProt	NX_Q9UJQ4
Antibodypedia	SALL4 antibodies

PROTEIN BROWSER

SALL4-001	SALL4-002	SALL4-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SALL4-001 ENSP00000217086 ENST00000217086	Q9UJQ4 [Direct mapping] Sal-like protein 4 Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Disease related genes Protein evidence (Ezkurdia et al 2014) Show all	GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0000792 [heterochromatin] GO:0001701 [in utero embryonic development] GO:0001833 [inner cell mass cell proliferation] GO:0001843 [neural tube closure] GO:0003281 [ventricular septum development] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0006355 [regulation of transcription, DNA-templated] GO:0006366 [transcription from RNA polymerase II promoter] GO:0007165 [signal transduction] GO:0007275 [multicellular organismal development] GO:0007507 [heart development] GO:0009888 [tissue development] GO:0019827 [stem cell population maintenance] GO:0021915 [neural tube development] GO:0030326 [embryonic limb morphogenesis] GO:0035019 [somatic stem cell population maintenance] GO:0043231 [intracellular membrane-bounded organelle] GO:0043234 [protein complex] GO:0043565 [sequence-specific DNA binding] GO:0044212 [transcription regulatory region DNA binding] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0046872 [metal ion binding] Show all	1053 aa 112.2 kDa	No	0
SALL4-002 ENSP00000379319 ENST00000395997	Q9UJQ4 [Direct mapping] Sal-like protein 4 Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Disease related genes Protein evidence (Ezkurdia et al 2014) Show all	GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005515 [protein binding] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0006355 [regulation of transcription, DNA-templated] GO:0006366 [transcription from RNA polymerase II promoter] GO:0007165 [signal transduction] GO:0007275 [multicellular organismal development] GO:0035019 [somatic stem cell population maintenance] GO:0043231 [intracellular membrane-bounded organelle] GO:0043565 [sequence-specific DNA binding] GO:0044212 [transcription regulatory region DNA binding] GO:0046872 [metal ion binding] Show all	616 aa 65.7 kDa	No	0
SALL4-201 ENSP00000360594 ENST00000371539	Q6Y8G5 [Direct mapping] SALL4C; Sal-like protein 4 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0005654 [nucleoplasm] GO:0046872 [metal ion binding] Show all	276 aa 29.4 kDa	No	0