The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
Subset of cells in red pulp, cells in molecular layer and granular layer of cerebellum and islet of Langerhans in pancreas showed strong cytoplasmic positivity. Leydig cells and heart muscle were moderately stained. Other normal tissues were negative.
Moderate cytoplasmic positivity was observed in thyroid, neuropil, granular and molecular layer of cerebellum along with subset of hematopoietic, neuronal and glial cells. Intercalated discs of heart myocytes were moderately stained. Remaining normal tissues were weakly stained or mostly negative.
Heart myocytes, granular layer of cerebellum, basal layer of skin epidermis and neuropil displayed moderate to strong cytoplasmic positivity. Remaining normal cells were negative.