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Several cases of skin and thyroid cancers along with a few lymphomas, squamous cell carcinomas, pancreatic, testicular and ovarian cancers showed moderate cytoplasmic and/or nuclear/membranous immunoreactivity. Cases of colorectal cancers displayed moderate to strong staining. Remaining cancers were weakly stained or negative.
Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
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GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0003677 [DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0003713 [transcription coactivator activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0006351 [transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0008016 [regulation of heart contraction] GO:0015630 [microtubule cytoskeleton] GO:0045171 [intercellular bridge] GO:0046872 [metal ion binding]
TMHMM predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014)
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GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0005634 [nucleus] GO:0006357 [regulation of transcription from RNA polymerase II promoter]
