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CDC37L1

GENERAL INFORMATION

Gene name

 CDC37L1

Gene description

 Cell division cycle 37-like 1

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in most tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data.

Reliability score

 Approved based on 1 antibody.
HPA021175
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 CDC37L1 (HGNC Symbol)

Synonyms

 CDC37B, FLJ20639, HARC

Description

 Cell division cycle 37-like 1 (HGNC Symbol)

Entrez gene summary

 CDC37L1 is a cytoplasmic phosphoprotein that exists in complex with HSP90 (HSPCA; MIM 140571) as well as several other proteins involved in HSP90-mediated protein folding (Scholz et al., 2001 [PubMed 11413142]).[supplied by OMIM, Mar 2008]

Chromosome

 9

Cytoband

 p24.1

Chromosome location (bp)

 4679559 - 4708398

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000106993 (version 83.38)

Entrez gene

 55664

UniProt

 Q7L3B6 (UniProt - Evidence at protein level)

neXtProt

 NX_Q7L3B6

Antibodypedia

 CDC37L1 antibodies

PROTEIN BROWSER
CDC37L1-001
CDC37L1-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
CDC37L1-001
ENSP00000371278
ENST00000381854
Q7L3B6 [Direct mapping]
Hsp90 co-chaperone Cdc37-like 1
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0006457 [protein folding]
GO:0031072 [heat shock protein binding]
GO:0050821 [protein stabilization]
GO:0051082 [unfolded protein binding]
GO:0051087 [chaperone binding]
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 337 aa
38.8 kDa 		No 0
CDC37L1-002
ENSP00000371282
ENST00000381858
B1AL69 [Direct mapping]
Hsp90 co-chaperone Cdc37-like 1
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005737 [cytoplasm]
GO:0006457 [protein folding]
GO:0031072 [heat shock protein binding]
GO:0050821 [protein stabilization]
GO:0051082 [unfolded protein binding]
GO:0051087 [chaperone binding]
Show all
 308 aa
35.6 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.