Fields »
ABOUT
HELP
BLOG
PTGES3

CANCER ATLAS

Gene description

 Prostaglandin E synthase 3 (cytosolic)

Protein class

 Enzymes, Plasma proteins, Predicted intracellular proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA038672
HPA038673
CAB034319

GENE INFORMATION

Gene name

 PTGES3 (HGNC Symbol)

Synonyms

 cPGES, p23, TEBP

Description

 Prostaglandin E synthase 3 (cytosolic) (HGNC Symbol)

Entrez gene summary

Chromosome

 12

Cytoband

 q13.3

Chromosome location (bp)

 56663341 - 56688408

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000110958 (version 83.38)

Entrez gene

 10728

UniProt

 Q15185 (UniProt - Evidence at protein level)

neXtProt

 NX_Q15185

Antibodypedia

 PTGES3 antibodies

PROTEIN BROWSER
PTGES3-001
PTGES3-002
PTGES3-003
PTGES3-004
PTGES3-006
PTGES3-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
PTGES3-001
ENSP00000262033
ENST00000262033
Q15185 [Direct mapping]
Prostaglandin E synthase 3
A0A024RB32 [Target identity:100%; Query identity:100%]
Prostaglandin E synthase 3 (Cytosolic), isoform CRA_a
Show all
Enzymes
   ENZYME proteins
   Isomerase
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000723 [telomere maintenance]
GO:0000781 [chromosome, telomeric region]
GO:0001516 [prostaglandin biosynthetic process]
GO:0003720 [telomerase activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005697 [telomerase holoenzyme complex]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006278 [RNA-dependent DNA replication]
GO:0007165 [signal transduction]
GO:0019369 [arachidonic acid metabolic process]
GO:0019371 [cyclooxygenase pathway]
GO:0034605 [cellular response to heat]
GO:0044281 [small molecule metabolic process]
GO:0050220 [prostaglandin-E synthase activity]
GO:0051082 [unfolded protein binding]
GO:0070062 [extracellular exosome]
GO:0070389 [chaperone cofactor-dependent protein refolding]
GO:1900034 [regulation of cellular response to heat]
Show all
 160 aa
18.7 kDa 		No 0
PTGES3-002
ENSP00000389090
ENST00000456859
B4DDC6 [Direct mapping]
Prostaglandin E synthase 3; cDNA FLJ59832, moderately similar to Prostaglandin E synthase 3 (EC 5.3.99.3)
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
Show all
 124 aa
14.6 kDa 		No 0
PTGES3-003
ENSP00000405299
ENST00000414274
Q15185 [Direct mapping]
Prostaglandin E synthase 3
Show all
Enzymes
   ENZYME proteins
   Isomerase
Predicted intracellular proteins
Plasma proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000723 [telomere maintenance]
GO:0000781 [chromosome, telomeric region]
GO:0001516 [prostaglandin biosynthetic process]
GO:0003720 [telomerase activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005697 [telomerase holoenzyme complex]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006278 [RNA-dependent DNA replication]
GO:0007165 [signal transduction]
GO:0019369 [arachidonic acid metabolic process]
GO:0019371 [cyclooxygenase pathway]
GO:0034605 [cellular response to heat]
GO:0044281 [small molecule metabolic process]
GO:0050220 [prostaglandin-E synthase activity]
GO:0051082 [unfolded protein binding]
GO:0070062 [extracellular exosome]
GO:0070389 [chaperone cofactor-dependent protein refolding]
GO:1900034 [regulation of cellular response to heat]
Show all
 130 aa
15 kDa 		No 0
PTGES3-004
ENSP00000414892
ENST00000448157
Q15185 [Direct mapping]
Prostaglandin E synthase 3
Show all
Enzymes
   ENZYME proteins
   Isomerase
Predicted intracellular proteins
Plasma proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000723 [telomere maintenance]
GO:0000781 [chromosome, telomeric region]
GO:0001516 [prostaglandin biosynthetic process]
GO:0003720 [telomerase activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005697 [telomerase holoenzyme complex]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006278 [RNA-dependent DNA replication]
GO:0007165 [signal transduction]
GO:0019369 [arachidonic acid metabolic process]
GO:0019371 [cyclooxygenase pathway]
GO:0034605 [cellular response to heat]
GO:0044281 [small molecule metabolic process]
GO:0050220 [prostaglandin-E synthase activity]
GO:0051082 [unfolded protein binding]
GO:0070062 [extracellular exosome]
GO:0070389 [chaperone cofactor-dependent protein refolding]
GO:1900034 [regulation of cellular response to heat]
Show all
 139 aa
16.5 kDa 		No 0
PTGES3-006
ENSP00000402385
ENST00000436399
Q15185 [Direct mapping]
Prostaglandin E synthase 3
Show all
Enzymes
   ENZYME proteins
   Isomerase
Predicted intracellular proteins
Plasma proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000723 [telomere maintenance]
GO:0000781 [chromosome, telomeric region]
GO:0001516 [prostaglandin biosynthetic process]
GO:0003720 [telomerase activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005697 [telomerase holoenzyme complex]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006278 [RNA-dependent DNA replication]
GO:0007165 [signal transduction]
GO:0019369 [arachidonic acid metabolic process]
GO:0019371 [cyclooxygenase pathway]
GO:0034605 [cellular response to heat]
GO:0044281 [small molecule metabolic process]
GO:0050220 [prostaglandin-E synthase activity]
GO:0051082 [unfolded protein binding]
GO:0070062 [extracellular exosome]
GO:0070389 [chaperone cofactor-dependent protein refolding]
GO:1900034 [regulation of cellular response to heat]
Show all
 127 aa
14.8 kDa 		No 0
PTGES3-201
ENSP00000482075
ENST00000614328
A0A087WYT3 [Direct mapping]
Prostaglandin E synthase 3
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005978 [glycogen biosynthetic process]
GO:0008283 [cell proliferation]
GO:0042921 [glucocorticoid receptor signaling pathway]
GO:0043588 [skin development]
GO:0060430 [lung saccule development]
Show all
 164 aa
19.2 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.