Cell atlas - SPSB2 - The Human Protein Atlas

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SPSB2

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	SPSB2
Gene description	SplA/ryanodine receptor domain and SOCS box containing 2
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	4
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	SPSB2 (HGNC Symbol)
Synonyms	GRCC9, SSB-2
Description	SplA/ryanodine receptor domain and SOCS box containing 2 (HGNC Symbol)
Entrez gene summary	This gene encodes encodes a suppressor of cytokine signaling (SOCS) family member, and it belongs to the subfamily of proteins containing a central SPRY (repeats in splA and RyR) domain and a C-terminal SOCS box. This gene is present in a gene-rich cluster on chromosome 12p13 in the vicinity of the CD4 antigen and triosephosphate isomerase genes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]
Chromosome	12
Cytoband	p13.31
Chromosome location (bp)	6870935 - 6889358
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000111671 (version 83.38)
Entrez gene	84727
UniProt	Q99619 (UniProt - Evidence at protein level)
neXtProt	NX_Q99619
Antibodypedia	SPSB2 antibodies

PROTEIN BROWSER

SPSB2-002	SPSB2-003	SPSB2-004	SPSB2-005

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SPSB2-002 ENSP00000428458 ENST00000432205	E5RIC2 [Direct mapping] SPRY domain-containing SOCS box protein 2 Show all	Predicted intracellular proteins Show all		82 aa 8.8 kDa	No	0
SPSB2-003 ENSP00000428338 ENST00000524270	Q99619 [Direct mapping] SPRY domain-containing SOCS box protein 2 Show all	Predicted intracellular proteins Show all	GO:0003674 [molecular_function] GO:0005515 [protein binding] GO:0005575 [cellular_component] GO:0005737 [cytoplasm] GO:0008150 [biological_process] GO:0016567 [protein ubiquitination] GO:0035556 [intracellular signal transduction] Show all	263 aa 28.6 kDa	No	0
SPSB2-004 ENSP00000430872 ENST00000523102	Q99619 [Direct mapping] SPRY domain-containing SOCS box protein 2 Show all	Predicted intracellular proteins Show all	GO:0003674 [molecular_function] GO:0005515 [protein binding] GO:0005575 [cellular_component] GO:0005737 [cytoplasm] GO:0008150 [biological_process] GO:0016567 [protein ubiquitination] GO:0035556 [intracellular signal transduction] Show all	263 aa 28.6 kDa	No	0
SPSB2-005 ENSP00000431037 ENST00000519357	Q99619 [Direct mapping] SPRY domain-containing SOCS box protein 2 Show all	Predicted intracellular proteins Show all	GO:0003674 [molecular_function] GO:0005515 [protein binding] GO:0005575 [cellular_component] GO:0005737 [cytoplasm] GO:0008150 [biological_process] GO:0016567 [protein ubiquitination] GO:0035556 [intracellular signal transduction] Show all	267 aa 28.6 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.