Expression of SLC25A16 in cancer - Summary

CANCER ATLAS

Gene description

Solute carrier family 25 (mitochondrial carrier), member 16

Protein class

Predicted intracellular proteins, Predicted membrane proteins, Transporters

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA044580

GENE INFORMATION
Gene name	SLC25A16 (HGNC Symbol)
Synonyms	D10S105E, GDA, HGT.1, ML7
Description	Solute carrier family 25 (mitochondrial carrier), member 16 (HGNC Symbol)
Entrez gene summary	This gene encodes a protein that contains three tandemly repeated mitochondrial carrier protein domains. The encoded protein is localized in the inner membrane and facilitates the rapid transport and exchange of molecules between the cytosol and the mitochondrial matrix space. This gene has a possible role in Graves' disease. [provided by RefSeq, Jul 2008]
Chromosome	10
Cytoband	q21.3
Chromosome location (bp)	68477999 - 68527474
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000122912 (version 83.38)
Entrez gene	8034
UniProt	P16260 (UniProt - Evidence at protein level)
neXtProt	NX_P16260
Antibodypedia	SLC25A16 antibodies

PROTEIN BROWSER

SLC25A16-002	SLC25A16-007

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SLC25A16-002 ENSP00000476815 ENST00000609923	P16260 [Direct mapping] Graves disease carrier protein Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005739 [mitochondrion] GO:0005743 [mitochondrial inner membrane] GO:0006766 [vitamin metabolic process] GO:0006767 [water-soluble vitamin metabolic process] GO:0006810 [transport] GO:0009108 [coenzyme biosynthetic process] GO:0015297 [antiporter activity] GO:0015939 [pantothenate metabolic process] GO:0016021 [integral component of membrane] GO:0044281 [small molecule metabolic process] GO:0055085 [transmembrane transport] Show all	332 aa 36.2 kDa	Yes	2
SLC25A16-007 ENSP00000477328 ENST00000608053	V9GZ24 [Direct mapping] Graves disease carrier protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	65 aa 6.9 kDa	No	0