Cell atlas - SLC25A16 - The Human Protein Atlas

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SLC25A16

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Mitochondria

Human cell
	Mitochondria

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GENERAL INFORMATION
Gene name	SLC25A16
Gene description	Solute carrier family 25 (mitochondrial carrier), member 16
Protein class	Predicted intracellular proteins Predicted membrane proteins Transporters
Predicted localization	Intracellular,Membrane
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the mitochondria.
RNA cell category	Mixed
Protein evidence	Evidence at protein level
Main location	Localized to the Mitochondria (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA036243
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the mitochondria.

Main location

Mitochondria (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA036243	PC-3	Mitochondria
	HPA036243	RT4	No staining
	HPA036243	U-2 OS	No staining

GENE INFORMATION
Gene name	SLC25A16 (HGNC Symbol)
Synonyms	D10S105E, GDA, HGT.1, ML7
Description	Solute carrier family 25 (mitochondrial carrier), member 16 (HGNC Symbol)
Entrez gene summary	This gene encodes a protein that contains three tandemly repeated mitochondrial carrier protein domains. The encoded protein is localized in the inner membrane and facilitates the rapid transport and exchange of molecules between the cytosol and the mitochondrial matrix space. This gene has a possible role in Graves' disease. [provided by RefSeq, Jul 2008]
Chromosome	10
Cytoband	q21.3
Chromosome location (bp)	68477999 - 68527474
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000122912 (version 83.38)
Entrez gene	8034
UniProt	P16260 (UniProt - Evidence at protein level)
neXtProt	NX_P16260
Antibodypedia	SLC25A16 antibodies

PROTEIN BROWSER

SLC25A16-002	SLC25A16-007

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SLC25A16-002 ENSP00000476815 ENST00000609923	P16260 [Direct mapping] Graves disease carrier protein Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005739 [mitochondrion] GO:0005743 [mitochondrial inner membrane] GO:0006766 [vitamin metabolic process] GO:0006767 [water-soluble vitamin metabolic process] GO:0006810 [transport] GO:0009108 [coenzyme biosynthetic process] GO:0015297 [antiporter activity] GO:0015939 [pantothenate metabolic process] GO:0016021 [integral component of membrane] GO:0044281 [small molecule metabolic process] GO:0055085 [transmembrane transport] Show all	332 aa 36.2 kDa	Yes	2
SLC25A16-007 ENSP00000477328 ENST00000608053	V9GZ24 [Direct mapping] Graves disease carrier protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	65 aa 6.9 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.