Expression of SLC35B3 in cancer - Summary

CANCER ATLAS

Gene description

Solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B3

Protein class

Predicted membrane proteins, Transporters

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

STAINING SUMMARY

HPA054661	HPA057801

GENE INFORMATION
Gene name	SLC35B3 (HGNC Symbol)
Synonyms	C6orf196, CGI-19, dJ453H5.1, PAPST2
Description	Solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B3 (HGNC Symbol)
Entrez gene summary	This gene is a member of the solute carrier family. The encoded protein is involved in the transport of 3-prime phosphoadenosine 5-prime phosphosulfate (PAPS) from the nucleus or the cytosol to the Golgi lumen. This gene has been reported to be expressed preferentially in the human colon tissues. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
Chromosome	6
Cytoband	p24.3
Chromosome location (bp)	8413068 - 8435483
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000124786 (version 83.38)
Entrez gene	51000
UniProt	Q9H1N7 (UniProt - Evidence at protein level)
neXtProt	NX_Q9H1N7
Antibodypedia	SLC35B3 antibodies

PROTEIN BROWSER

SLC35B3-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SLC35B3-001 ENSP00000368981 ENST00000379660	Q9H1N7 [Direct mapping] Adenosine 3'-phospho 5'-phosphosulfate transporter 2 A0A024R008 [Target identity:100%; Query identity:100%] Solute carrier family 35, member B3, isoform CRA_c Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0002230 [positive regulation of defense response to virus by host] GO:0005739 [mitochondrion] GO:0005794 [Golgi apparatus] GO:0005975 [carbohydrate metabolic process] GO:0006805 [xenobiotic metabolic process] GO:0016021 [integral component of membrane] GO:0030203 [glycosaminoglycan metabolic process] GO:0043231 [intracellular membrane-bounded organelle] GO:0044281 [small molecule metabolic process] GO:0050427 [3'-phosphoadenosine 5'-phosphosulfate metabolic process] GO:0050428 [3'-phosphoadenosine 5'-phosphosulfate biosynthetic process] GO:0055085 [transmembrane transport] GO:0098779 [mitophagy in response to mitochondrial depolarization] Show all	401 aa 44.6 kDa	No	>9