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SLC35B3

GENERAL INFORMATION

Gene name

 SLC35B3

Gene description

 Solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B3

Protein class

 Predicted membrane proteins
Transporters

Predicted localization

 Membrane

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in most tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Pending external verification.

Reliability score

 Approved based on 2 antibodies.
HPA054661 , HPA057801
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 SLC35B3 (HGNC Symbol)

Synonyms

 C6orf196, CGI-19, dJ453H5.1, PAPST2

Description

 Solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B3 (HGNC Symbol)

Entrez gene summary

 This gene is a member of the solute carrier family. The encoded protein is involved in the transport of 3-prime phosphoadenosine 5-prime phosphosulfate (PAPS) from the nucleus or the cytosol to the Golgi lumen. This gene has been reported to be expressed preferentially in the human colon tissues. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]

Chromosome

 6

Cytoband

 p24.3

Chromosome location (bp)

 8413068 - 8435483

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000124786 (version 83.38)

Entrez gene

 51000

UniProt

 Q9H1N7 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9H1N7

Antibodypedia

 SLC35B3 antibodies

PROTEIN BROWSER
SLC35B3-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
SLC35B3-001
ENSP00000368981
ENST00000379660
Q9H1N7 [Direct mapping]
Adenosine 3'-phospho 5'-phosphosulfate transporter 2
A0A024R008 [Target identity:100%; Query identity:100%]
Solute carrier family 35, member B3, isoform CRA_c
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Transporters
   Electrochemical Potential-driven transporters
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   >9TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane]
GO:0002230 [positive regulation of defense response to virus by host]
GO:0005739 [mitochondrion]
GO:0005794 [Golgi apparatus]
GO:0005975 [carbohydrate metabolic process]
GO:0006805 [xenobiotic metabolic process]
GO:0016021 [integral component of membrane]
GO:0030203 [glycosaminoglycan metabolic process]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0044281 [small molecule metabolic process]
GO:0050427 [3'-phosphoadenosine 5'-phosphosulfate metabolic process]
GO:0050428 [3'-phosphoadenosine 5'-phosphosulfate biosynthetic process]
GO:0055085 [transmembrane transport]
GO:0098779 [mitophagy in response to mitochondrial depolarization]
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 401 aa
44.6 kDa 		No >9

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.