Cell atlas - GNRH2 - The Human Protein Atlas

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GNRH2

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	GNRH2
Gene description	Gonadotropin-releasing hormone 2
Protein class	Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	4
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Mixed
Protein evidence	Evidence at transcript level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	GNRH2
Synonyms
Description	Gonadotropin-releasing hormone 2 (HGNC Symbol)
Entrez gene summary	This gene encodes a secreted peptide hormone and member of the gonadotropin-releasing hormone (GnRH) family of proteins. The encoded protein regulates reproductive function by stimulating the production and release of the gonadotropins follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The encoded protein may inhibit endometrial, ovarian, prostate, and breast cancer cell proliferation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
Chromosome	20
Cytoband	p13
Chromosome location (bp)	3043622 - 3045747
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000125787 (version 83.38)
Entrez gene	2797
UniProt	O43555 (UniProt - Evidence at transcript level)
neXtProt	NX_O43555
Antibodypedia	GNRH2 antibodies

PROTEIN BROWSER

GNRH2-001	GNRH2-002	GNRH2-003	GNRH2-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GNRH2-001 ENSP00000245983 ENST00000245983	O43555 [Direct mapping] Progonadoliberin-2 Gonadoliberin-2 GnRH-associated peptide 2 Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0000003 [reproduction] GO:0005179 [hormone activity] GO:0005183 [gonadotropin hormone-releasing hormone activity] GO:0005576 [extracellular region] GO:0005615 [extracellular space] GO:0007165 [signal transduction] GO:0007275 [multicellular organismal development] GO:0031530 [gonadotropin-releasing hormone receptor binding] GO:0046883 [regulation of hormone secretion] Show all	120 aa 12.9 kDa	Yes	0
GNRH2-002 ENSP00000369704 ENST00000380346	O43555 [Direct mapping] Progonadoliberin-2 Gonadoliberin-2 GnRH-associated peptide 2 Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0000003 [reproduction] GO:0005179 [hormone activity] GO:0005183 [gonadotropin hormone-releasing hormone activity] GO:0005576 [extracellular region] GO:0005615 [extracellular space] GO:0007165 [signal transduction] GO:0007275 [multicellular organismal development] GO:0031530 [gonadotropin-releasing hormone receptor binding] GO:0046883 [regulation of hormone secretion] Show all	112 aa 12.2 kDa	Yes	0
GNRH2-003 ENSP00000369705 ENST00000380347	O43555 [Direct mapping] Progonadoliberin-2 Gonadoliberin-2 GnRH-associated peptide 2 Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0000003 [reproduction] GO:0005179 [hormone activity] GO:0005183 [gonadotropin hormone-releasing hormone activity] GO:0005576 [extracellular region] GO:0005615 [extracellular space] GO:0007165 [signal transduction] GO:0007275 [multicellular organismal development] GO:0031530 [gonadotropin-releasing hormone receptor binding] GO:0046883 [regulation of hormone secretion] Show all	113 aa 12.2 kDa	Yes	0
GNRH2-004 ENSP00000352003 ENST00000359100	O43555 [Direct mapping] Progonadoliberin-2 Gonadoliberin-2 GnRH-associated peptide 2 Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0000003 [reproduction] GO:0005179 [hormone activity] GO:0005183 [gonadotropin hormone-releasing hormone activity] GO:0005576 [extracellular region] GO:0005615 [extracellular space] GO:0007165 [signal transduction] GO:0007275 [multicellular organismal development] GO:0031530 [gonadotropin-releasing hormone receptor binding] GO:0046883 [regulation of hormone secretion] Show all	113 aa 12.2 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.