Tissue expression of GNRH2 - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

GNRH2

TISSUE

CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	GNRH2
Gene description	Gonadotropin-releasing hormone 2
Protein class	Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	4
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Mixed
GTEx:	Mixed
FANTOM5:	Tissue enhanced (epididymis)

Protein evidence

Evidence at transcript level

Protein expression

Estimation of protein expression could not be performed. View primary data.

DATA RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Secreted protein, tissue location of RNA and protein might differ and correlation is complex.
Reliability score	Uncertain based on 1 antibody. HPA004338
	SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

N/A

Caudate

N/A

N/A

Cerebellum

N/A

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

N/A

Bronchus

N/A

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

N/A

Skin

N/A

Skin

N/A

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Mixed
GTEx dataset Organ Expression Alphabetical RNA tissue category: Mixed
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (epididymis)

GENE INFORMATION
Gene name	GNRH2
Synonyms
Description	Gonadotropin-releasing hormone 2 (HGNC Symbol)
Entrez gene summary	This gene encodes a secreted peptide hormone and member of the gonadotropin-releasing hormone (GnRH) family of proteins. The encoded protein regulates reproductive function by stimulating the production and release of the gonadotropins follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The encoded protein may inhibit endometrial, ovarian, prostate, and breast cancer cell proliferation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
Chromosome	20
Cytoband	p13
Chromosome location (bp)	3043622 - 3045747
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000125787 (version 83.38)
Entrez gene	2797
UniProt	O43555 (UniProt - Evidence at transcript level)
neXtProt	NX_O43555
Antibodypedia	GNRH2 antibodies

PROTEIN BROWSER

GNRH2-001	GNRH2-002	GNRH2-003	GNRH2-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GNRH2-001 ENSP00000245983 ENST00000245983	O43555 [Direct mapping] Progonadoliberin-2 Gonadoliberin-2 GnRH-associated peptide 2 Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0000003 [reproduction] GO:0005179 [hormone activity] GO:0005183 [gonadotropin hormone-releasing hormone activity] GO:0005576 [extracellular region] GO:0005615 [extracellular space] GO:0007165 [signal transduction] GO:0007275 [multicellular organismal development] GO:0031530 [gonadotropin-releasing hormone receptor binding] GO:0046883 [regulation of hormone secretion] Show all	120 aa 12.9 kDa	Yes	0
GNRH2-002 ENSP00000369704 ENST00000380346	O43555 [Direct mapping] Progonadoliberin-2 Gonadoliberin-2 GnRH-associated peptide 2 Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0000003 [reproduction] GO:0005179 [hormone activity] GO:0005183 [gonadotropin hormone-releasing hormone activity] GO:0005576 [extracellular region] GO:0005615 [extracellular space] GO:0007165 [signal transduction] GO:0007275 [multicellular organismal development] GO:0031530 [gonadotropin-releasing hormone receptor binding] GO:0046883 [regulation of hormone secretion] Show all	112 aa 12.2 kDa	Yes	0
GNRH2-003 ENSP00000369705 ENST00000380347	O43555 [Direct mapping] Progonadoliberin-2 Gonadoliberin-2 GnRH-associated peptide 2 Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0000003 [reproduction] GO:0005179 [hormone activity] GO:0005183 [gonadotropin hormone-releasing hormone activity] GO:0005576 [extracellular region] GO:0005615 [extracellular space] GO:0007165 [signal transduction] GO:0007275 [multicellular organismal development] GO:0031530 [gonadotropin-releasing hormone receptor binding] GO:0046883 [regulation of hormone secretion] Show all	113 aa 12.2 kDa	Yes	0
GNRH2-004 ENSP00000352003 ENST00000359100	O43555 [Direct mapping] Progonadoliberin-2 Gonadoliberin-2 GnRH-associated peptide 2 Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0000003 [reproduction] GO:0005179 [hormone activity] GO:0005183 [gonadotropin hormone-releasing hormone activity] GO:0005576 [extracellular region] GO:0005615 [extracellular space] GO:0007165 [signal transduction] GO:0007275 [multicellular organismal development] GO:0031530 [gonadotropin-releasing hormone receptor binding] GO:0046883 [regulation of hormone secretion] Show all	113 aa 12.2 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.