Expression of FLRT1 in cancer - Summary

CANCER ATLAS

Gene description

Fibronectin leucine rich transmembrane protein 1

Protein class

Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA054589

GENE INFORMATION
Gene name	FLRT1 (HGNC Symbol)
Synonyms	MGC21624, SPG68
Description	Fibronectin leucine rich transmembrane protein 1 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the fibronectin leucine rich transmembrane protein (FLRT) family. The family members may function in cell adhesion and/or receptor signalling. Their protein structures resemble small leucine-rich proteoglycans found in the extracellular matrix. The encoded protein shares sequence similarity with two other family members, FLRT2 and FLRT3. This gene is expressed in kidney and brain. [provided by RefSeq, Jul 2008]
Chromosome	11
Cytoband	q13.1
Chromosome location (bp)	64103188 - 64119173
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000126500 (version 83.38)
Entrez gene	23769
UniProt	Q9NZU1 (UniProt - Evidence at protein level)
neXtProt	NX_Q9NZU1
Antibodypedia	FLRT1 antibodies

PROTEIN BROWSER

FLRT1-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FLRT1-001 ENSP00000246841 ENST00000246841	Q9NZU1 [Direct mapping] Leucine-rich repeat transmembrane protein FLRT1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0005057 [receptor signaling protein activity] GO:0005104 [fibroblast growth factor receptor binding] GO:0005515 [protein binding] GO:0005578 [proteinaceous extracellular matrix] GO:0005615 [extracellular space] GO:0005789 [endoplasmic reticulum membrane] GO:0005887 [integral component of plasma membrane] GO:0005911 [cell-cell junction] GO:0005925 [focal adhesion] GO:0007155 [cell adhesion] GO:0008543 [fibroblast growth factor receptor signaling pathway] GO:0016358 [dendrite development] GO:0030659 [cytoplasmic vesicle membrane] GO:0030674 [protein binding, bridging] GO:0031410 [cytoplasmic vesicle] GO:0032809 [neuronal cell body membrane] GO:0035556 [intracellular signal transduction] GO:0044306 [neuron projection terminus] GO:0048471 [perinuclear region of cytoplasm] GO:0051965 [positive regulation of synapse assembly] GO:1990138 [neuron projection extension] Show all	674 aa 74.1 kDa	No	1