Fields »
ABOUT
HELP
BLOG
FLRT1

GENERAL INFORMATION

Gene name

 FLRT1

Gene description

 Fibronectin leucine rich transmembrane protein 1

Protein class

 Predicted membrane proteins

Predicted localization

 Membrane

Number of transcripts

 1
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enhanced (cerebral cortex)
GTEx:Mixed

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in several tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data.

Reliability score

 Uncertain based on 1 antibody.
HPA054589
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (cerebral cortex)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed

GENE INFORMATION

Gene name

 FLRT1 (HGNC Symbol)

Synonyms

 MGC21624, SPG68

Description

 Fibronectin leucine rich transmembrane protein 1 (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the fibronectin leucine rich transmembrane protein (FLRT) family. The family members may function in cell adhesion and/or receptor signalling. Their protein structures resemble small leucine-rich proteoglycans found in the extracellular matrix. The encoded protein shares sequence similarity with two other family members, FLRT2 and FLRT3. This gene is expressed in kidney and brain. [provided by RefSeq, Jul 2008]

Chromosome

 11

Cytoband

 q13.1

Chromosome location (bp)

 64103188 - 64119173

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000126500 (version 83.38)

Entrez gene

 23769

UniProt

 Q9NZU1 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9NZU1

Antibodypedia

 FLRT1 antibodies

PROTEIN BROWSER
FLRT1-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
FLRT1-001
ENSP00000246841
ENST00000246841
Q9NZU1 [Direct mapping]
Leucine-rich repeat transmembrane protein FLRT1
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Show all
GO:0005057 [receptor signaling protein activity]
GO:0005104 [fibroblast growth factor receptor binding]
GO:0005515 [protein binding]
GO:0005578 [proteinaceous extracellular matrix]
GO:0005615 [extracellular space]
GO:0005789 [endoplasmic reticulum membrane]
GO:0005887 [integral component of plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005925 [focal adhesion]
GO:0007155 [cell adhesion]
GO:0008543 [fibroblast growth factor receptor signaling pathway]
GO:0016358 [dendrite development]
GO:0030659 [cytoplasmic vesicle membrane]
GO:0030674 [protein binding, bridging]
GO:0031410 [cytoplasmic vesicle]
GO:0032809 [neuronal cell body membrane]
GO:0035556 [intracellular signal transduction]
GO:0044306 [neuron projection terminus]
GO:0048471 [perinuclear region of cytoplasm]
GO:0051965 [positive regulation of synapse assembly]
GO:1990138 [neuron projection extension]
Show all
 674 aa
74.1 kDa 		No 1

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.