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FLRT1

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GENERAL INFORMATION

Gene name

 FLRT1

Gene description

 Fibronectin leucine rich transmembrane protein 1

Protein class

 Predicted membrane proteins

Predicted localization

 Membrane

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

Summary

RNA cell category

 Cell line enhanced (SH-SY5Y, THP-1, SCLC-21H)

Protein evidence

 Evidence at protein level

Main location

 Not available

DATA RELIABILITY

Reliability score

 Pending cell analysis.

ASSAYS
RNA expression

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (SH-SY5Y, THP-1, SCLC-21H)
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

GENE INFORMATION

Gene name

 FLRT1 (HGNC Symbol)

Synonyms

 MGC21624, SPG68

Description

 Fibronectin leucine rich transmembrane protein 1 (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the fibronectin leucine rich transmembrane protein (FLRT) family. The family members may function in cell adhesion and/or receptor signalling. Their protein structures resemble small leucine-rich proteoglycans found in the extracellular matrix. The encoded protein shares sequence similarity with two other family members, FLRT2 and FLRT3. This gene is expressed in kidney and brain. [provided by RefSeq, Jul 2008]

Chromosome

 11

Cytoband

 q13.1

Chromosome location (bp)

 64103188 - 64119173

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000126500 (version 83.38)

Entrez gene

 23769

UniProt

 Q9NZU1 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9NZU1

Antibodypedia

 FLRT1 antibodies

PROTEIN BROWSER
FLRT1-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
FLRT1-001
ENSP00000246841
ENST00000246841
Q9NZU1 [Direct mapping]
Leucine-rich repeat transmembrane protein FLRT1
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Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Show all
GO:0005057 [receptor signaling protein activity]
GO:0005104 [fibroblast growth factor receptor binding]
GO:0005515 [protein binding]
GO:0005578 [proteinaceous extracellular matrix]
GO:0005615 [extracellular space]
GO:0005789 [endoplasmic reticulum membrane]
GO:0005887 [integral component of plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005925 [focal adhesion]
GO:0007155 [cell adhesion]
GO:0008543 [fibroblast growth factor receptor signaling pathway]
GO:0016358 [dendrite development]
GO:0030659 [cytoplasmic vesicle membrane]
GO:0030674 [protein binding, bridging]
GO:0031410 [cytoplasmic vesicle]
GO:0032809 [neuronal cell body membrane]
GO:0035556 [intracellular signal transduction]
GO:0044306 [neuron projection terminus]
GO:0048471 [perinuclear region of cytoplasm]
GO:0051965 [positive regulation of synapse assembly]
GO:1990138 [neuron projection extension]
Show all
 674 aa
74.1 kDa 		No 1

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.