We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
Fields »
 

Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Tissue

Detectable

Cell line

Detectable

Category

Score

Score

Score

Antibodies

Column

 
 
ABOUT
HELP
BLOG
  • THE HUMAN PROTEOME
  • THE HUMAN TISSUES
  • THE HUMAN CELL
  • PROTEIN CLASSES
  • PROTEIN EVIDENCE
    • NEWS
    • BLOG
    • EVENTS
    • PRESS ROOM
    • LEARN
    • DICTIONARY
    • METHODS
    • CELL LINES
  • THE PROJECT
  • INTRODUCTION
  • ORGANIZATION
  • PUBLICATIONS
  • PUBLICATION DATA
  • ANTIBODY SUBMISSION
  • ANTIBODY AVAILABILITY
  • LINKS
  • CONTACT
  • TECHNICAL DATA
  • ANTIBODY VALIDATION
  • ASSAYS & ANNOTATION
  • DISCLAIMER
  • DOWNLOADABLE DATA
  • HELP & FAQ
  • LICENCE & CITATION
  • PRIVACY STATEMENT
  • RELEASE HISTORY
HSPA2
  • TISSUE

  • CELL

  • CANCER

TISSUE ATLAS PRIMARY DATA
MOUSE BRAIN

GENE/PROTEIN

Antibody validation


Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

HSPA2

Gene description

Heat shock 70kDa protein 2

Protein class

Cancer-related genes
Plasma proteins
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

2
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Tissue enhanced (testis)
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Cytoplasmic and nuclear expression of varying intensity in most tissues.

DATA RELIABILITY

Data reliability
description

Antibody staining mainly consistent with RNA expression data. Caution, targets protein from more than one gene. Pending external verification.

Reliability score

Approved based on 2 antibodies.
HPA000798 , HPA052504
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
Cerebral cortex
Hippocampus
N/A
Caudate
N/A
Cerebellum
N/A
Endocrine tissues
Thyroid gland
Parathyroid gland
Adrenal gland
Bone marrow & immune system
Appendix
Bone marrow
Lymph node
Tonsil
Spleen
Muscle tissues
Heart muscle
Skeletal muscle
Smooth muscle
Lung
Nasopharynx
N/A
Bronchus
N/A
Lung
Liver & gallbladder
Liver
Gallbladder
Pancreas
Pancreas
Gastrointestinal tract
Oral mucosa
N/A
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Colon
Rectum
Kidney & urinary bladder
Kidney
Urinary bladder
Male tissues
Testis
Epididymis
Prostate
Seminal vesicle
Female tissues
Breast
Vagina
N/A
Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Adipose & soft tissue
Adipose tissue
Soft tissue
N/A
Skin
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Skin

PROTEIN EXPRESSION OVERVIEW

Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (testis)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

HSPA2

Synonyms

Description

Heat shock 70kDa protein 2 (HGNC Symbol)

Entrez gene summary

Chromosome

14

Cytoband

q23.3

Chromosome location (bp)

64535905 - 64546173

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000126803 (version 83.38)

Entrez gene

3306

UniProt

P54652 (UniProt - Evidence at protein level)

neXtProt

NX_P54652

Antibodypedia

HSPA2 antibodies

PROTEIN BROWSER

HSPA2-001
HSPA2-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HSPA2-001
ENSP00000378199
ENST00000394709
P54652 [Direct mapping]
Heat shock-related 70 kDa protein 2
A0A024R6B5 [Target identity:100%; Query identity:100%]
Heat shock 70kDa protein 2, isoform CRA_a
Show all
Predicted intracellular proteins
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000795 [synaptonemal complex]
GO:0001673 [male germ cell nucleus]
GO:0001934 [positive regulation of protein phosphorylation]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005634 [nucleus]
GO:0005739 [mitochondrion]
GO:0005829 [cytosol]
GO:0006986 [response to unfolded protein]
GO:0007140 [male meiosis]
GO:0007141 [male meiosis I]
GO:0007286 [spermatid development]
GO:0009408 [response to heat]
GO:0009409 [response to cold]
GO:0009986 [cell surface]
GO:0016020 [membrane]
GO:0019899 [enzyme binding]
GO:0031662 [positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle]
GO:0032781 [positive regulation of ATPase activity]
GO:0036128 [CatSper complex]
GO:0042026 [protein refolding]
GO:0043209 [myelin sheath]
GO:0051082 [unfolded protein binding]
GO:0051861 [glycolipid binding]
GO:0070062 [extracellular exosome]
GO:0070194 [synaptonemal complex disassembly]
GO:0072562 [blood microparticle]
GO:0090084 [negative regulation of inclusion body assembly]
GO:1901896 [positive regulation of calcium-transporting ATPase activity]
Show all
639 aa
70 kDa
No 0
HSPA2-201
ENSP00000247207
ENST00000247207
P54652 [Direct mapping]
Heat shock-related 70 kDa protein 2
A0A024R6B5 [Target identity:100%; Query identity:100%]
Heat shock 70kDa protein 2, isoform CRA_a
Show all
Predicted intracellular proteins
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005634 [nucleus]
GO:0005829 [cytosol]
GO:0006986 [response to unfolded protein]
GO:0007140 [male meiosis]
GO:0009408 [response to heat]
GO:0009409 [response to cold]
GO:0016020 [membrane]
GO:0019899 [enzyme binding]
GO:0036128 [CatSper complex]
GO:0042026 [protein refolding]
GO:0051082 [unfolded protein binding]
GO:0070062 [extracellular exosome]
GO:0072562 [blood microparticle]
GO:0090084 [negative regulation of inclusion body assembly]
Show all
639 aa
70 kDa
No 0

Contact

  • BLOG
  • PRESS ROOM
  • contact@proteinatlas.org

The Project

  • INTRODUCTION
  • ORGANIZATION
  • PUBLICATIONS
  • DOWNLOADABLE DATA

The Human Protein Atlas

  • ANTIBODY AVAILABILITY
  • LICENCE & CITATION
  • HELP & FAQ
The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.