Cell atlas - FIBCD1 - The Human Protein Atlas

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FIBCD1

TISSUE

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CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cell Junctions

Human cell
	Plasma Membrane

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GENERAL INFORMATION
Gene name	FIBCD1
Gene description	Fibrinogen C domain containing 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the cell junctions.
RNA cell category	Cell line enhanced (MCF7, RPTEC TERT1, U-2 OS)
Protein evidence	Evidence at protein level
Main location	Localized to the Cell Junctions (supported)

DATA RELIABILITY
Reliability score	Supported based on 1 antibody. HPA055353
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (MCF7, RPTEC TERT1, U-2 OS) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the cell junctions.

Main location

Cell Junctions (supported)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA055353	MCF7	Cell Junctions
	HPA055353	U-2 OS	No staining
	HPA055353	U-251 MG	No staining

GENE INFORMATION
Gene name	FIBCD1 (HGNC Symbol)
Synonyms	FLJ14810
Description	Fibrinogen C domain containing 1 (HGNC Symbol)
Entrez gene summary	FIBCD1 is a conserved type II transmembrane endocytic receptor that binds chitin and is located primarily in the intestinal brush border (Schlosser et al., 2009 [PubMed 19710473]).[supplied by OMIM, Apr 2010]
Chromosome	9
Cytoband	q34.12
Chromosome location (bp)	130902438 - 130939286
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000130720 (version 83.38)
Entrez gene	84929
UniProt	Q8N539 (UniProt - Evidence at protein level)
neXtProt	NX_Q8N539
Antibodypedia	FIBCD1 antibodies

PROTEIN BROWSER

FIBCD1-001	FIBCD1-002	FIBCD1-003	FIBCD1-004	FIBCD1-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FIBCD1-001 ENSP00000361413 ENST00000372338	Q8N539 [Direct mapping] Fibrinogen C domain-containing protein 1 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] GO:0008061 [chitin binding] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0046872 [metal ion binding] Show all	461 aa 50.7 kDa	No	0
FIBCD1-002 ENSP00000361412 ENST00000372337	A3KFJ8 [Direct mapping] Fibrinogen C domain-containing protein 1 Show all	Predicted intracellular proteins Show all		303 aa 33.9 kDa	No	0
FIBCD1-003 ENSP00000395319 ENST00000444139	H0Y4Y8 [Direct mapping] Fibrinogen C domain-containing protein 1 Show all	Predicted intracellular proteins Show all		310 aa 33.3 kDa	No	0
FIBCD1-004 ENSP00000393894 ENST00000451466	X6RDH7 [Direct mapping] Fibrinogen C domain-containing protein 1 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Show all	GO:0016021 [integral component of membrane] Show all	289 aa 31.1 kDa	No	0
FIBCD1-201 ENSP00000414501 ENST00000448616	Q8N539 [Direct mapping] Fibrinogen C domain-containing protein 1 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] GO:0008061 [chitin binding] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0046872 [metal ion binding] Show all	461 aa 50.7 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.