Tissue expression of CNDP2 - Summary - The Human Protein Atlas

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CNDP2

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TISSUE

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CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	CNDP2
Gene description	CNDP dipeptidase 2 (metallopeptidase M20 family)
Protein class	Enzymes Plasma proteins Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	18
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

General cytoplasmic expression, highly abundant in renal tubules and most glandular epithelia.

DATA RELIABILITY
Data reliability description	Antibody staining consistent with RNA expression data.
Reliability score	Supported based on 3 antibodies. HPA036898 , HPA036899 , CAB026196
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	CNDP2 (HGNC Symbol)
Synonyms	CN2, CPGL, FLJ10830, HsT2298, PEPA
Description	CNDP dipeptidase 2 (metallopeptidase M20 family) (HGNC Symbol)
Entrez gene summary	CNDP2, also known as tissue carnosinase and peptidase A (EC 3.4.13.18), is a nonspecific dipeptidase rather than a selective carnosinase (Teufel et al., 2003 [PubMed 12473676]).[supplied by OMIM, Mar 2008]
Chromosome	18
Cytoband	q22.3
Chromosome location (bp)	74495816 - 74523454
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000133313 (version 83.38)
Entrez gene	55748
UniProt	Q96KP4 (UniProt - Evidence at protein level)
neXtProt	NX_Q96KP4
Antibodypedia	CNDP2 antibodies

PROTEIN BROWSER

CNDP2-001	CNDP2-004	CNDP2-006	CNDP2-007	CNDP2-010	CNDP2-011	CNDP2-012	CNDP2-014	CNDP2-016	CNDP2-017	CNDP2-018	CNDP2-019	CNDP2-020	CNDP2-021	CNDP2-022	CNDP2-024	CNDP2-025	CNDP2-031

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CNDP2-001 ENSP00000325548 ENST00000324262	Q96KP4 [Direct mapping] Cytosolic non-specific dipeptidase V9HWE5 [Target identity:100%; Query identity:100%] CNDP dipeptidase 2 (Metallopeptidase M20 family), isoform CRA_c; Epididymis secretory protein Li 13 Show all	Enzymes ENZYME proteins Hydrolases Peptidases Metallopeptidases Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000096 [sulfur amino acid metabolic process] GO:0004180 [carboxypeptidase activity] GO:0005829 [cytosol] GO:0006508 [proteolysis] GO:0006750 [glutathione biosynthetic process] GO:0006805 [xenobiotic metabolic process] GO:0008152 [metabolic process] GO:0008233 [peptidase activity] GO:0008237 [metallopeptidase activity] GO:0016787 [hydrolase activity] GO:0016805 [dipeptidase activity] GO:0034641 [cellular nitrogen compound metabolic process] GO:0034701 [tripeptidase activity] GO:0044281 [small molecule metabolic process] GO:0046872 [metal ion binding] GO:0070062 [extracellular exosome] GO:1901687 [glutathione derivative biosynthetic process] Show all	475 aa 52.9 kDa	No	0
CNDP2-004 ENSP00000462311 ENST00000579847	Q96KP4 [Direct mapping] Cytosolic non-specific dipeptidase V9HWE5 [Target identity:100%; Query identity:100%] CNDP dipeptidase 2 (Metallopeptidase M20 family), isoform CRA_c; Epididymis secretory protein Li 13 Show all	Enzymes ENZYME proteins Hydrolases Peptidases Metallopeptidases Predicted intracellular proteins Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000096 [sulfur amino acid metabolic process] GO:0004180 [carboxypeptidase activity] GO:0005829 [cytosol] GO:0006508 [proteolysis] GO:0006750 [glutathione biosynthetic process] GO:0006805 [xenobiotic metabolic process] GO:0008152 [metabolic process] GO:0008237 [metallopeptidase activity] GO:0016787 [hydrolase activity] GO:0016805 [dipeptidase activity] GO:0034641 [cellular nitrogen compound metabolic process] GO:0034701 [tripeptidase activity] GO:0044281 [small molecule metabolic process] GO:0046872 [metal ion binding] GO:0070062 [extracellular exosome] GO:1901687 [glutathione derivative biosynthetic process] Show all	475 aa 52.9 kDa	No	0
CNDP2-006 ENSP00000325756 ENST00000324301	Q96KP4 [Direct mapping] Cytosolic non-specific dipeptidase Show all	Enzymes ENZYME proteins Hydrolases Peptidases Metallopeptidases Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000096 [sulfur amino acid metabolic process] GO:0004180 [carboxypeptidase activity] GO:0005829 [cytosol] GO:0006750 [glutathione biosynthetic process] GO:0006805 [xenobiotic metabolic process] GO:0008152 [metabolic process] GO:0008237 [metallopeptidase activity] GO:0016787 [hydrolase activity] GO:0016805 [dipeptidase activity] GO:0034641 [cellular nitrogen compound metabolic process] GO:0034701 [tripeptidase activity] GO:0044281 [small molecule metabolic process] GO:0046872 [metal ion binding] GO:0070062 [extracellular exosome] GO:1901687 [glutathione derivative biosynthetic process] Show all	391 aa 43.8 kDa	No	0
CNDP2-007 ENSP00000482227 ENST00000584768	A0A087WYZ1 [Direct mapping] Cytosolic non-specific dipeptidase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0008152 [metabolic process] GO:0016787 [hydrolase activity] Show all	157 aa 17.3 kDa	No	0
CNDP2-010 ENSP00000462034 ENST00000579624	J3KRJ8 [Direct mapping] Cytosolic non-specific dipeptidase Show all	MEMSAT3 predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		109 aa 12.5 kDa	No	0
CNDP2-011 ENSP00000464151 ENST00000581272	J3QRD0 [Direct mapping] Cytosolic non-specific dipeptidase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0008152 [metabolic process] GO:0016787 [hydrolase activity] Show all	134 aa 14.9 kDa	No	0
CNDP2-012 ENSP00000464214 ENST00000580672	J3QRH4 [Direct mapping] Cytosolic non-specific dipeptidase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0006508 [proteolysis] GO:0008152 [metabolic process] GO:0008237 [metallopeptidase activity] GO:0016787 [hydrolase activity] Show all	204 aa 22.4 kDa	No	0
CNDP2-014 ENSP00000463314 ENST00000583203	J3QL02 [Direct mapping] Cytosolic non-specific dipeptidase Show all	SCAMPI predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		138 aa 15.2 kDa	No	0
CNDP2-016 ENSP00000463702 ENST00000581513	J3QLU1 [Direct mapping] Cytosolic non-specific dipeptidase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		123 aa 13.7 kDa	No	0
CNDP2-017 ENSP00000463816 ENST00000577600	J3QQN6 [Direct mapping] Cytosolic non-specific dipeptidase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		89 aa 9.9 kDa	No	0
CNDP2-018 ENSP00000464122 ENST00000579583	J3QRA8 [Direct mapping] Cytosolic non-specific dipeptidase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		138 aa 15.9 kDa	No	0
CNDP2-019 ENSP00000462673 ENST00000583216	J3KSV5 [Direct mapping] Cytosolic non-specific dipeptidase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0008152 [metabolic process] GO:0016787 [hydrolase activity] Show all	149 aa 16.5 kDa	No	0
CNDP2-020 ENSP00000462626 ENST00000581912	J3KSS4 [Direct mapping] Cytosolic non-specific dipeptidase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		55 aa 6.4 kDa	No	0
CNDP2-021 ENSP00000463182 ENST00000582589	J3QKQ0 [Direct mapping] Cytosolic non-specific dipeptidase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0008152 [metabolic process] GO:0016787 [hydrolase activity] Show all	128 aa 14.3 kDa	No	0
CNDP2-022 ENSP00000463222 ENST00000583785	J3QKT2 [Direct mapping] Cytosolic non-specific dipeptidase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0006508 [proteolysis] GO:0008152 [metabolic process] GO:0008237 [metallopeptidase activity] GO:0016787 [hydrolase activity] Show all	249 aa 27.7 kDa	No	0
CNDP2-024 ENSP00000461941 ENST00000582666	J3KRD5 [Direct mapping] Cytosolic non-specific dipeptidase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0008152 [metabolic process] GO:0016787 [hydrolase activity] Show all	88 aa 9.4 kDa	No	0
CNDP2-025 ENSP00000479635 ENST00000577355	A0A087WVS2 [Direct mapping] Cytosolic non-specific dipeptidase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0008152 [metabolic process] GO:0016787 [hydrolase activity] Show all	124 aa 13.3 kDa	No	0
CNDP2-031 ENSP00000464014 ENST00000584613	J3QR27 [Direct mapping] Cytosolic non-specific dipeptidase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		122 aa 13.6 kDa	No	0

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The Human Protein Atlas

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